Results 71 to 80 of about 879,007 (253)
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
The Right to Free and Compulsory Education: Delivering the promise of the law
, 2013 In 2009, the Right of Children to Free and Compulsory Education Act (RTE) established the government's obligation to guarantee eight years of free, quality education to all children aged 6 to 14 years.
Singh, Shyam +2 more
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Molecular Oncology, EarlyView.Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source
Education and Human Rights: “Education As Everybody’s Right”
, 2019 Human beings are not always fully aware of their rights and what this implies to be able to enjoy them. That is why the need to research on the population’s knowledge of education as a right for all arose. Specifically, the research was carried out in the community of the southern border area, near the National University Brunca Region Campus, Coto ...
Angulo Ureña, Julio +1 more
openaire +1 more source
The right to education of children with disabilities in Côte d'Ivoire
reservedThe right to education is the key to a better life for every child and the foundation of any strong society - yet far too many children - including those with disabilities - are still being left behind.
KOUADIO, AMANI LAETITIA LAURENE
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Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
The right to education in Scotland.
, 2001 An overview of the right to education in Scots law and how the rights and duties within the state system might be expected to ...
Macfarlane, Lesley-Anne Barnes
core