Results 111 to 120 of about 793,126 (355)

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Tackling Language Obstacles in Cross-Border Litigation: The European Order for Payment and the European Small Claims Procedure Approach [PDF]

open access: yes, 2013
In cross-border litigation, language differences are one of the main obstacles preventing parties from taking action and defending their rights. The Regulations creating a European Order for Payment Procedure (EOP) and establishing a European Small ...
Ontanu, E.A. (Elena)   +1 more
core  

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

Does the placement of the accused at court undermine the right to a fair trial? [PDF]

open access: yes, 2016
The UK Government has recently launched an ambitious reform of the court estate across England and Wales, including the closure of 86 courts and signi cant investment in new technologies. The time is right to rethink how courts of the future should look,
Rossner, Meredith
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

THE CONCEPT „INDEPENDENT AND IMPRATIAL TRIBUNAL” IN THE PRACTICE OF THE EUROPEAN COURT OF HUMAN RIGHTS

open access: yesPravo, 2012
One of important principle every democratic state is rule of law. The rule of law in countries of democratic tradition, so-called countries of western democracy, is not questioned any more.
Nihad Ukić
doaj  

The rights of journalistic newsgathering during demonstrations [PDF]

open access: yes, 2018
In a case about a Ukrainian journalist being arrested during an anti-globalisation protest in Russia, the European Court of Human Rights (ECtHR) in Butkevich v.
Simons, Daniel, Voorhoof, Dirk
core   +1 more source

Homologous expression and purification of human HAX‐1 for structural studies

open access: yesFEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

The Use of Videoconferencing at Trial and Its Effects on the Rights of the Defense: A Study of the Future Regulation in The Netherlands

open access: yesTilburg Law Review
This article focuses on the proposed regulation of videoconferencing in criminal procedure in the new Dutch Code of Criminal Procedure, from the perspective of the defendant’s right to a fair trial as guaranteed in Article 6 ECHR.
Marianne Hirsch Ballin, Tess Castelijn
doaj   +1 more source

Забезпечення реалізації права на здоров'я в діяльності Європейського суду з прав людини [PDF]

open access: yes, 2012
Сажієнко Н. В. Забезпечення реалізації права на здоров'я в діяльності Європейського суду з прав людини /Н. В. Сажієнко // Актуальні проблеми політики : зб. наук. пр. / редкол. : С. В. Ківалов (голов. ред..), Л. І. Кормич (заст. голов. ред..), Ю.
Sazhienko, N.   +2 more
core  

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