Results 121 to 130 of about 5,732,009 (360)

Vital Signs: Metro Boston's Arts and Cultural Nonprofits 1999 and 2004 [PDF]

open access: yes, 2007
Examines four "vital signs," or categories of data, to gauge the health of the area's arts and cultural nonprofit organizations in 1999-2004: a supportive environment, an innovative marketplace, an engaged audience, and the right-sized ...
Ann McQueen, Susan Nelson
core  

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

Minding The Climate Gap: What's at Stake if California's Climate Law isn't Done Right and Right Away [PDF]

open access: yes, 2010
Minding the Climate Gap: What's at Stake if California's Climate Law isn't Done Right and Right Away details how incentivizing the reduction of greenhouse gases -- which cause climate change -- from facilities operating in the most polluted neighborhoods
James Sadd   +3 more
core  

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

THE RIGHT TO ENVIRONMENT [PDF]

open access: yes
This study refers to the fundamental right of the human being to have a healthy, ecologically balanced environment as well as to the necessity of recognizing and guaranteeing this right.
Carmen Elena Radu, Viorica Paraschivescu
core  

HELP in New Jersey: From Right-to-Know to Right-to-Act [PDF]

open access: yes, 1990
[Excerpt] Since 1987 the New Jersey Right-to-Know-and-Act Coalition has been working to extend the rights of citizens and workers to take an active part in decisions vital to their health and safety.
Jeffrey, Edith K.
core   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

Treating rare diseases with justice: Implications of a human rights-based approach

open access: yesRevista Tecnológica
The importance of health for social justice has increased since the end of the 20th century, particularly following the recognition in the 1995 Copenhagen Declaration that "people are entitled to a healthy and productive life in harmony with the ...
Stéphanie Dagron
doaj   +1 more source

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