Results 221 to 230 of about 5,702,046 (400)

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

open access: yesMolecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha   +10 more
wiley   +1 more source

Challenges in Promoting the Interdependence of all Human Rights [PDF]

open access: yesHealth and Human Rights, 2020
Dainius Pūras
doaj  

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

A right to health denied: access to oral healthcare during the war on the Gaza Strip. [PDF]

open access: yesBMJ Glob Health
Almadhoon H   +4 more
europepmc   +1 more source

Decrypting cancer's spatial code: from single cells to tissue niches

open access: yesMolecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik   +4 more
wiley   +1 more source

Health systems and the right to health: an assessment of 194 countries [PDF]

open access: green, 2008
Gunilla Backman   +13 more
openalex   +1 more source

COVID-19 vaccine equity and the right to health for displaced Venezuelans in Latin America. [PDF]

open access: yesPLOS Glob Public Health, 2023
Hill DC   +7 more
europepmc   +1 more source

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