Results 61 to 70 of about 2,340,883 (315)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Service provision and barriers to care for homeless people with mental health problems across 14 European capital cities

, 2012
Background Mental health problems are disproportionately higher amongst homeless people. Many barriers exist for homeless people with mental health problems in accessing treatment yet little research has been done on service provision and quality of care
Greacen, Tim, Straßmayr, Christa, Jacek Moskalewicz, Soares, Joaquim, Kluge Ulrike, Barry Margaret M, Priebe, Stefan, Schene, AH, Holcnerova, Petra, Gaddini, Andrea, Soares Joaquim J F, Diaz-Olalla, Jose Manuel, Petra Holcnerová, Soares, JJF, Gaddini Andrea, Barry, Margaret M, Aleksandra Matanov, Margaret M Barry, Barry, Margaret M., Barros, H, Greacen, T, Greacen Tim, Canavan, Reamonn, Díaz-Olalla José, Barros, Henrique, Kluge, U, Schene, Aart, Moskalewicz, Jacek, Aart H Schene, Manuel Diaz-Olalla, J, Priebe, S, Matanov, Aleksandra, Schene, Aart H., Nicaise Pablo, Canavan Réamonn, Nicaise, Pablo, Soares, Joaquim J. F.,, Henrique Barros, Canavan, R, Ulrike Kluge, Strassmayr, C, Nicaise, P, Réamonn Canavan, Barros Henrique, Barry, MM, Tim Greacen, Soares, Joaquim J. F., Joaquim J F Soares, Priebe Stefan, Barry, Margaret, Gabor Edina, Stefan Priebe, Matanov Aleksandra, Gabor, E, José Manuel Díaz-Olalla, Holcnerova, P, Holcnerová Petra, Matanov, A, Schene Aart H, Moskalewicz Jacek, Christa Straßmayr, Andrea Gaddini, Schene, Aart H, Pablo Nicaise, Gabor, Edina, Kluge, Ulrike, Edina Gabor, Soares, Joaquim J F, Moskalewicz, J, Straßmayr Christa, Gaddini, A   +70 more
core   +1 more source

Good practice in mental health care for socially marginalised groups in Europe: a qualitative study of expert views in 14 countries [PDF]

, 2012
Background Socially marginalised groups tend to have higher rates of mental disorders than the general population and can be difficult to engage in health care. Providing mental health care for these groups represents a particular challenge, and evidence
Greacen, Tim, Macassa, Gloria,, Straßmayr, Christa, Jacek Moskalewicz, Kluge Ulrike, Macassa Gloria, Barry Margaret M, Gloria Macassa, Priebe, Stefan, Schene, AH, Gaddini, Andrea, Petra Holcnerová, Macassa, Gloria, Gaddini Andrea, Barry, Margaret M, Aleksandra Matanov, Margaret M Barry, Barry, Margaret M., Moskalewicz, J,, Barry, Margaret M,, Barros, H, Greacen, T, Schor, Ruth, Greacen Tim, Ruth Schor, Díaz-Olalla José, Matanov, Alexandra,, Moskalewicz, Jasec,, Barros, Henrique, Barry, Margareth M,, Kluge, U, Holcnerová, Petra,, Barros, Henrique,, Moskalewicz, Jacek, Lorant Vincent, Matanov, Alexandra, Aart H Schene, Schor Ruth, Priebe, S, Manuel Diaz-Olalla, J, Matanov, Aleksandra, Holcnerová, Petra, Schene, Aart H., Schene, Aart H,, Henrique Barros, Gaddini, Andrea,, Ulrike Kluge, Díaz-Olalla, José Manuel, Priebe, Stefan,, Strassmayr, C, Lorant, V, Lorant, V,, Barros Henrique, Barry, MM, Vincent Lorant, Tim Greacen, Macassa, G, Greacen, Tim,, Priebe Stefan, Gaddini, A,, Díaz-Olalla, José Manuel,, Gabor Edina, Stefan Priebe, Matanov Aleksandra, Gabor, E, Lorant, Vincent,, José Manuel Díaz-Olalla, Holcnerova, P, Holcnerová Petra, Matanov, A, Straßmayr, Christa,, Schene Aart H, Schor, R, Moskalewicz Jacek, Kluge, Ulrike,, Christa Straßmayr, Andrea Gaddini, Kluge, U,, Schene, Aart H, Gabor, Edina, Kluge, Ulrike, Lorant, Vincent, Edina Gabor, Moskalewicz, J, Straßmayr Christa, Gabor, Edina,, Gaddini, A, Schor, Ruth,, Schene, AH,   +88 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Community Right to Know Annual Report (1993), 1995

, 1995
This is a summary of the information submitted in 1994 by New Jersey businesses covered by state and federal New Jersey Worker and Community Right to Know (W&CRTK) Act and/or the federal Emergency Planning and Amendments and Reauthorization Act (EPCRA ...

core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Guideline on the management of occupational and non-occupational exposure to the human immunodeficiency virus and recommendations for post-exposure prophylaxis: 2015 Update

Southern African Journal of HIV Medicine, 2015
This guideline is an update of the post-exposure prophylaxis (PEP) guideline published by the Southern African HIV Clinicians Society in 2008. It updates the recommendations on the use of antiretroviral medications to prevent individuals who have been ...
Michelle Moorhouse, Linda G. Bekker, Vivian Black, Francesca Conradie, Beth Harley, Pauline Howell, Gary Maartens, Tari Papavarnavas, Kevin Rebe, Gillian Sorour, Francois Venter, Carole L. Wallis   +11 more
doaj   +1 more source

Access to Medicines and the Right to (Cultural) Life

, 2010
Published version available from: http://www.ashgate.com/isbn/9780754677611This groundbreaking book is the first collection to investigate together the law, political science and ethical perspectives on the right and value of ...
Gibson, J
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Revising a right to food road map—perspectives of Australian key informants

Australian and New Zealand Journal of Public Health
Objective: In Australia, an estimated 1 in 10 households experiences food insecurity. The objective of this study was to devise a visual synthesis to summarise the activities, processes and principles that support the right to food for everyone in ...
Rebecca Lindberg, Vivien Yii, Elizabeth Millen, Stephanie Godrich   +3 more
doaj   +1 more source