Results 101 to 110 of about 94,952,183 (338)

Community Right to Know Annual Report (1992), 1994

open access: yes, 1994
Community Right to Know Annual Report with an introduction, community right to know survey for 1992, and New Jersey Release and Pollution Prevention Report for 1992.New Jersey business owners and operators who are regulated by the New Jersey Worker and ...

core   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

Fighting for the Right to Act in New Jersey [report], 1992

open access: yes, 1992
A report on the nation's first state labor/environmental ''right-to-act" legislative campaign to win new rights for workers and neighbors to prevent toxic and other hazards.

core  

Comparing the paths of Hedgehog release in artificial and natural settings

open access: yesFEBS Letters, EarlyView.
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Extending the Right to Life Under the International Covenant on Civil and Political Rights: General Comment 36

open access: yes, 2019
The following commentary analyses General Comment 36 on the right to life in Article 6 of the International Covenant on Civil and Political Rights (ICCPR),1 which was adopted by the treaty’s monitoring body, the Human Rights Committee (HRC), in October ...
Joseph, Sarah Louise
core   +1 more source

“Right to life” in monotheistic religions [PDF]

open access: yesComparative Theology, 2015
" Right to life" as the fundamental rights of every person, from the beginning, has been important in the different schools of thought and religions, especially the monotheistic religions.
Muhammad Reza Ehsani Mutlaq   +1 more
doaj  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

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