Results 231 to 240 of about 87,749,872 (302)

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers, Yaqiao Wei, Dinesh K. Deelchand, Adam Berrington, Young Woo Park, Guita Banan, Michal Povazan, Jens T. Rosenberg, André J. W. van der Kouwe, Tetsuo Ashizawa, Khalaf O. Bushara, Chiadi U. Onyike, Sub H. Subramony, Jeremy D. Schmahmann, Brian J. Soher, Peter B. Barker, Thomas H. Mareci, Eva‐Maria Ratai, Lynn E. Eberly, Gülin Öz   +19 more
wiley   +1 more source

Sustainable design of jewelry materials through green polymer and low impact processing strategies. [PDF]

Front Chem
Wang Q, Li D, Guo N.
europepmc   +1 more source

Electroencephalographic Normalization as a Biomarker of Clinical Recovery in Down Syndrome Regression Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Down syndrome regression disorder is a syndrome characterized by subacute loss of cognitive, behavioral, and functional abilities in individuals with Down syndrome. Electroencephalography abnormalities are frequently observed during evaluation, but it remains unclear whether these findings represent a dynamic marker of disease ...
Jonathan D. Santoro, Mackenzie Silverman, Maeve C. Lucas, Mariam M. Yousuf, Samuel T. Otey, Stella V. Gray, Brittany Jordan, Madeline D. Kahan, Latanya D. Agurs, Michelle Van Hirtum Das, Deborah Holder, Devin King, Eileen A. Quinn, Ryan Kammeyer, Michael S. Rafii   +14 more
wiley   +1 more source

T1 Over Squared Proton Density Ratio to Characterize Multiple Sclerosis Lesions

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Differentiating remyelinated from demyelinated lesions in MS remains challenging without histological confirmation. This study introduces the T1‐to‐PD2 ratio (TPR) imaging approach and evaluates its ability to characterize MS lesions alongside other quantitative MRI (qMRI) metrics. Methods Thirty individuals with MS (mean age: 47.5 ± 
Sarah J. Wright, Scotty G. McKay, Jean Ramos Bou, Fen Bao, Vivian B. Truong, Chenyang Li, Li Jiang, Anza B. Memon, E. Mark Haacke, Yulin Ge, Yongsheng Chen   +10 more
wiley   +1 more source

The global inverse fractional conductivity problem. [PDF]

Calc Var Partial Differ Equ
Covi G, Railo J, Zimmermann P.
europepmc   +1 more source

Application of the Plan-Do-Check-Act Management Model to Violence Risk Management in a Psychiatric Ward: Impact on Patient Safety and Nurse-Patient Relationships. [PDF]

Neuropsychiatr Dis Treat
Li J, Niu H, Liu X, Lei Z, Li H, Cheng Y, Du H, Wang Y.   +7 more
europepmc   +1 more source

Left-Right Consistency and Quantification of Craniofacial Asymmetry by Two Fully Automatic AI-Powered Three-Dimensional Cephalometry Systems on CBCT. [PDF]

Diagnostics (Basel)
Khabadze Z, Mordanov O, Wehbe A.
europepmc   +1 more source

Error Injection in Task-Based Image Quality Pipelines: What Regression Testing Cannot Catch, and Why Neither Internal Identities nor Closed-Form References Suffice Alone. [PDF]

J Imaging
Yamamoto S.
europepmc   +1 more source

Rerum Novarum: Educational resource to promote occupational health and rights in the industrial age of artificial intelligence. [PDF]

J Educ Health Promot
Persaud E.
europepmc   +1 more source