Results 31 to 40 of about 166,612 (219)
Republika Srpska Krajina and the right of peoples to self-determination [PDF]
Istorija 20. Veka, 2018 The collapse of the Berlin Wall witnessed a renaissance for the romantic theory of self-determination in that it underpinned a flurry of claims to statehood, especially in Eastern Europe. Nowhere was this more vividly illustrated than in the Balkan lands
Peter Radan
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
The Right to Self-Determination in Islam and Current International law [PDF]
پژوهش تطبیقی حقوق اسلام و غرب, 2016 One of the basic principles of contemporary international law is the principle of self-determination on the basis of witch all persons and states can administrate and lead their own affairs in different fields of political, economic and social .
Manuchehr Tavassoli Naini +1 more
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Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Implementation of Digital Data Erasure
University of Vienna Law ReviewAdopting an interdisciplinary perspective, this article examines data erasure by comparing the legal notion of data erasure to its definition in computer science as well as its applicability to digital data.
Yann Conti, Yann Schoenenberger
doaj +1 more source
A New Political Status for the Basque Country? [PDF]
Journal on Ethnopolitics and Minority Issues in Europe, 2013 The Basque Country can be said to have entered a new post-violence political scenario in 2012. In this context, a new opportunity for debating about the political status of the Country re-emerges.
Eduardo Ruiz Vieytez
doaj
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source