Results 41 to 50 of about 552,218 (303)

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Recovering the Right to the City in Post Pandemic-What about sacred spaces?

open access: yes, 2021
Architecture and urban design represent one of the most complex scenarios when it comes to imaging the new city that could flourish after the COVID-19 pandemic.
PETERCI, Emel
core  

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Delaware City School 1952

open access: yes, 1952
Students of the Delaware City School in 1952. From left to right: Barbara Ann Costanqo, Frank Pasquino,?,
Unknown
core   +5 more sources

Espaço público e “nova urbanidade” no contexto do direito á cidade

open access: yesConfins, 2013
The challengeof thinkingthe city in itsspatial perspectiveoffersknowledge thatinvolves the constructionofa theory ofsocio-spatial urban practice, in ordertoreveal thesense of realityas a whole andtheopportunitiesthat are emerginginthehorizonfor everyday ...
Ana Fani Alessandri Carlos
doaj   +1 more source

Women and cities. The conquest of urban space

open access: yesFrontiers in Sociology, 2023
In the city of the Nineteenth-century, transformed by the values of the French revolution and by the modernity, women did not have yet full citizenship.
Letizia Carrera, Marina Castellaneta
doaj   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

Right to the City: New York City Policy Platform [PDF]

open access: yes, 2009
To address the gaps in PlaNYC and to create a set of economic development principles rooted in community needs, RTTC-NYC developed this citywide, grassroots policy platform.

core  

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Identifying the Factors Influencing the Presence and Participation of Women in Urban Space from View of Right to the City

open access: yesتحقيقات جغرافيايی, 2018
One of the dimensions of democracy is the homological, responsive and welcoming spaces. Power in space includes a variety of features and different aspects.
Maryam farahzad   +3 more
doaj  

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