Results 41 to 50 of about 552,218 (303)
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Recovering the Right to the City in Post Pandemic-What about sacred spaces?
Architecture and urban design represent one of the most complex scenarios when it comes to imaging the new city that could flourish after the COVID-19 pandemic.
PETERCI, Emel
core
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Students of the Delaware City School in 1952. From left to right: Barbara Ann Costanqo, Frank Pasquino,?,
Unknown
core +5 more sources
Espaço público e “nova urbanidade” no contexto do direito á cidade
The challengeof thinkingthe city in itsspatial perspectiveoffersknowledge thatinvolves the constructionofa theory ofsocio-spatial urban practice, in ordertoreveal thesense of realityas a whole andtheopportunitiesthat are emerginginthehorizonfor everyday ...
Ana Fani Alessandri Carlos
doaj +1 more source
Women and cities. The conquest of urban space
In the city of the Nineteenth-century, transformed by the values of the French revolution and by the modernity, women did not have yet full citizenship.
Letizia Carrera, Marina Castellaneta
doaj +1 more source
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
Right to the City: New York City Policy Platform [PDF]
To address the gaps in PlaNYC and to create a set of economic development principles rooted in community needs, RTTC-NYC developed this citywide, grassroots policy platform.
core
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
One of the dimensions of democracy is the homological, responsive and welcoming spaces. Power in space includes a variety of features and different aspects.
Maryam farahzad +3 more
doaj

