Results 71 to 80 of about 157,911 (268)

Massage‐Mimicking Nanosheets Mechanically Reorganize Inter‐organelle Contacts to Restore Mitochondrial Functions in Parkinson's Disease

open access: yesAdvanced Science, EarlyView.
Parkinson's disease (PD) progression is aggravated by disrupted inter‐organelle contacts, which are influenced by mechanical forces. NanoMassage, 200 nm PEGylated black phosphorus nanosheets, deliver targeted mechanical stimulation to neural cells.
Tianqi Li   +12 more
wiley   +1 more source

Impact of bridging with left ventricular assist device on right ventricular function following heart transplantation

open access: yesESC Heart Failure, 2022
Aims Patients awaiting orthotopic heart transplantation (OHT) can be bridged utilizing a left ventricular assist device (LVAD) that reduces left ventricular filling pressures, decreases pulmonary artery wedge pressure, and maintains adequate cardiac ...
Annika Ingvarsson   +9 more
doaj   +1 more source

Semantic-aware Temporal Channel-wise Attention for Cardiac Function Assessment [PDF]

open access: yesarXiv, 2023
Cardiac function assessment aims at predicting left ventricular ejection fraction (LVEF) given an echocardiogram video, which requests models to focus on the changes in the left ventricle during the cardiac cycle. How to assess cardiac function accurately and automatically from an echocardiogram video is a valuable topic in intelligent assisted ...
arxiv  

Cardiomyocyte‐Enriched USP20 Ameliorates Pathological Cardiac Hypertrophy by Targeting STAT3 Deubiquitination

open access: yesAdvanced Science, EarlyView.
Cardiomyocyte‐enriched USP20 regulates the K63‐linked ubiquitination of STAT3, and the cardiomyocyte‐specific USP20‐STAT3‐CARM1 axis exerts a protective role in cardiac hypertrophy. Targeting USP20 through cardiac‐specific gene therapy presents a promising strategy for the treatment of cardiac hypertrophy.
Lingfeng Zhong   +15 more
wiley   +1 more source

Multi-scale simulation of thrombus formation at LVAD inlet cannula connection: Importance of Virchow's triad [PDF]

open access: yesarXiv, 2020
As pump thrombosis is reduced in current-generation ventricular assist devices (VAD), adverse events such as bleeding or stroke remain at unacceptable rates. Thrombosis around the VAD inlet cannula (IC) has been highlighted as a possible source of stroke events.
arxiv  

Comorbid CAD and Ventricular Hypertrophy Compromise The Perfusion of Myocardial Tissue at Subcritical Stenosis of Epicardial Coronaries [PDF]

open access: yes, 2018
BACKGROUND: Most studies of CAD revascularization have been based on and reported according to angiographic criteria which don't consider the relation between the resulting effective flow distal to the stenosis and the demand of a hypertrophied myocardial tissue.
arxiv   +1 more source

Novel Electroactive Therapeutic Platforms for Cardiac Arrhythmia Management

open access: yesAdvanced Science, EarlyView.
Electroactive platforms offer promising applications in cardiac arrhythmia. Based on their energy sources and mechanisms, electroactive platforms are categorized into i) direct electrical stimulation, ii) self‐powered electroactive systems, iii) physical stimuli‐mediated electroactive systems, and iv) conductive systems, and their applications in ...
Juwei Yang   +4 more
wiley   +1 more source

Different ECLS Pump Configurations for Temporary Right Ventricular Assist Device in LVAD Patients: A Retrospective Case–Control Study

open access: yesLife
Background: Acute right ventricular failure is a critical complication after left ventricular assist device (LVAD) implantation, often managed with a temporary paracorporeal right ventricular assist device (RVAD). This study examined three extracorporeal
Dragan Opacic   +13 more
doaj   +1 more source

Right ventricular failure following left ventricular assist device implantation is associated with a preoperative pro-inflammatory response

open access: yesJournal of Cardiothoracic Surgery, 2019
Background Systemic inflammation during implant of a durable left ventricular assist device (LVAD) may contribute to adverse outcomes. We investigated the association of the preoperative inflammatory markers with subsequent right ventricular failure (RVF)
Paul C. Tang   +7 more
doaj   +1 more source

Automatic Cardiac Disease Assessment on cine-MRI via Time-Series Segmentation and Domain Specific Features [PDF]

open access: yes, 2017
Cardiac magnetic resonance imaging improves on diagnosis of cardiovascular diseases by providing images at high spatiotemporal resolution. Manual evaluation of these time-series, however, is expensive and prone to biased and non-reproducible outcomes.
arxiv   +1 more source

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