Results 31 to 40 of about 156,606 (263)
Background Heart failure (HF) is a major health problem. Cardiac and renal diseases interact in a complex bidirectional manner in both acute and chronic settings.
Ahmed Aly Obiedallah +3 more
doaj +1 more source
Mechanisms of Transplant Right Ventricular Dysfunction
Right ventricular (RV) dysfunction remains the leading cause of early mortality after cardiac transplantation. The effect of brain death and subsequent hypothermic cardioplegic arrest and storage on subsequent post-transplant right ventricular function was examined.Right ventricular dysfunction in the donor heart usually is attributed to failure of the
P, Van Trigt +3 more
openaire +3 more sources
Background: The importance of right–left ventricular interactions is increasingly recognized in patients with congenital heart disease. Interventions to improve right ventricular volume/pressure overloading may result in improvement of left ventricular ...
James Wiley +5 more
doaj +1 more source
Heart failure with preserved ejection fraction (HFpEF) currently has no therapies that improve mortality. Right ventricular dysfunction and pulmonary hypertension are common in HFpEF, and thought to be driven by obesity and metabolic syndrome.
Vineet Agrawal +12 more
doaj +1 more source
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin +12 more
wiley +1 more source
Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende +26 more
wiley +1 more source
Assessment of right ventricular function by echocardiography in patients with chronic heart failure
Background: The main focus of most of the studies in heart failure (HF) is the assessment of the left ventricular functions, while the right ventricle was much less studied.
Viola William, Wael El Kilany
doaj +1 more source
Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett +8 more
wiley +1 more source
Right Ventricular-pulmonary Arterial Coupling in Pulmonary Hypertension: Application Advances
Prognosis in pulmonary hypertension is closely associated with right heart function. In the early stage of pulmonary hypertension, the right ventricle can maintain the normal blood flow of the pulmonary circulation by increasing its contractility. As the
DUAN Anqi +4 more
doaj +1 more source
Circulatory support for right ventricular dysfunction
New modes of circulatory support for right ventricular dysfunction have recently been described. The present study compared the effectiveness of pulmonary artery balloon counterpulsation with a right ventricular assist device for support of surgically induced right ventricular dysfunction.
G K, Jett, A L, Picone, R E, Clark
openaire +2 more sources

