Results 221 to 230 of about 205,036 (308)

Development of an efficient mice model of cancer‐associated cardiac cachexia

Animal Models and Experimental Medicine, EarlyView.
This work establishes a preclinical framework for targeting ubiquitin pathways to mitigate the morbidity of cancer‐related cardiopathy. Our integrated approach delineates a hierarchical progression from subcellular dysfunction to macroscopic cardiac deterioration. These findings mechanistically link tumor‐induced cachexia to cardiac dysfunction through
Shijie Xiong, Huiting Zheng, Teng Wu, Jing Tan, Tongsheng Huang, Conghui Shen, Yuanjun Ji, Mengying Liu, Junhong Wan, Weibin Cai   +9 more
wiley   +1 more source

Erratum for "Use of Indices Combining Diastolic and Systolic Tissue Doppler Variables to Evaluate Right Ventricular Function in Dogs With Pulmonary Stenosis". [PDF]

J Vet Intern Med
europepmc   +1 more source

Changes in hemodynamics of pulmonary artery using Flowire in a canine model of acute pulmonary thromboembolism

Animal Models and Experimental Medicine, EarlyView.
This study investigated changes in pulmonary artery hemodynamics using a Flowire catheter and evaluated the accuracy of Doppler echocardiography in dogs with acute pulmonary thromboembolism (PTE). Ten healthy beagles were anesthetized, and acute pulmonary hypertension (PH) was induced by injecting 300‐μm dextran microspheres.
Tomohiko Yoshida, Katsuhiro Matsuura, Akiko Uemura, Ryou Tanaka   +3 more
wiley   +1 more source

Left ventricular function and long-term right ventricular pacing in patients with atrial fibrillation following atrioventricular node ablation

, 2003
Cevher Özcan, Paul A. Friedman, David O. Hodge, Bernard J. Gersh, David L. Hayes, Stephen C. Hammill, Win K. Shen   +6 more
openalex   +1 more source

Longitudinal Analysis of Neuroradiological Biomarkers for Fragile X‐Associated Tremor/Ataxia Syndrome and Implications for Clinical Trials

Annals of Neurology, EarlyView.
Objective The objective of this study was to show the capacity of structural brain magnetic resonance imaging (MRI) measures to serve as monitoring biomarkers for Fragile X‐Associated Tremor/Ataxia Syndrome (FXTAS). Methods From 2 longitudinal studies of male FMR1 premutation carriers, 2 brain MRI scans were selected from each participant, collected ...
David Hessl, Jun Yi Wang, Glenda Espinal, Ellery Santos, Flora Tassone, Randi J. Hagerman, Susan M. Rivera   +6 more
wiley   +1 more source

Is Right Ventricle-to-Left Ventricle Diameter Ratio, A Static Parameter Measured by Computed Tomography Pulmonary Angiography, An Effective Index of Right Ventricular Function? [PDF]

Anatol J Cardiol
Naser A.
europepmc   +1 more source

HCN2‐Associated Neurodevelopmental Disorders: Data from Patients and Xenopus Cell Models

Annals of Neurology, EarlyView.
Objective We aimed to characterize the phenotypic spectrum and functional consequences associated with variants in HCN2, encoding for the hyperpolarization‐activated cyclic nucleotide (HCN) gated channel 2. Methods GeneMatcher facilitated the recruitment of 21 individuals with HCN2 variants from 15 unrelated families, carrying HCN2 variants.
Clara Houdayer, A. Marie Phillips, Marie Chabbert, Jennifer Bourreau, Reza Maroofian, Henry Houlden, Kay Richards, Nebal Waill Saadi, Eliška Dad'ová, Patrick Van Bogaert, Mailys Rupin, Boris Keren, Perrine Charles, Thomas Smol, Audrey Riquet, Lynn Pais, Anne O'Donnell‐Luria, Grace E. VanNoy, Allan Bayat, Rikke S Møller, Kern Olofsson, Rami Abou Jamra, Steffen Syrbe, Majed Dasouki, Laurie H. Seaver, Jennifer A. Sullivan, Vandana Shashi, Fowzan S. Alkuraya, Alexis F. Poss, J. Edward Spence, Rhonda E. Schnur, Ian C. Forster, Chaseley E. Mckenzie, Cas Simons, Min Wang, Penny Snell, Kavitha Kothur, Michael Buckley, Tony Roscioli, Noha Elserafy, Benjamin Dauriat, Vincent Procaccio, Daniel Henrion, Guy Lenaers, Estelle Colin, Nienke E. Verbeek, Koen L. Van Gassen, Claire Legendre, Dominique Bonneau, Christopher A. Reid, Katherine B. Howell, Alban Ziegler, Christian Legros   +52 more
wiley   +1 more source

Water‐Soluble Molecular Wires for Membrane Potential Imaging

Angewandte Chemie, EarlyView.
Fully water‐soluble fluorescent rosamine‐based amphiphilic molecular wires were developed for imaging membrane potentials. The performance of the probes was evaluated in single cardiomyocytes, murine pituitary gland, and islets of Langerhans.
Mirna El Khatib, Margret A. Fye, Keita Uchida, Ana L. Obaid, Thomas Troxler, Dylan Valente, Brian M. Salzberg, Benjamin Prosser, Irina N. Kaverina, Sergei A. Vinogradov   +9 more
wiley   +2 more sources

Echocardiographic Assessment of Right Ventricular Function in Patients With Liver Cirrhosis. [PDF]

Cureus
Enenche AA, Kweki AG, Aiwuyo HO, Nevolina A, Akinti OM, Perry JC, Ayinalem Y, Osarenkhoe JO, Ukenenye E, Poluyi CO, Danbauchi Sulei S.   +10 more
europepmc   +1 more source

The Scale of Neurodegeneration in Moderate‐to‐Severe Traumatic Brain Injury: A Systematic Review of Longitudinal Studies

Annals of Neurology, EarlyView.
Synthesis of Literature: Neurodegeneration in Moderate‐Severe TBI. Objective Although moderate‐to‐severe traumatic brain injury (msTBI) was once considered a static neural event following resolution of acute injuries, numerous studies now demonstrate progressive losses to volume and white matter integrity in the months and years postinjury, leading to ...
Bhanu Sharma, Leanne Monteiro, Alana Changoor, Brenda Colella, Robin Green   +4 more
wiley   +1 more source