Results 171 to 180 of about 2,531,746 (315)

QualityRights in medical education to reduce coercion in mental health in Colombia: instrument validation and quasi-experimental study. [PDF]

BJPsych Open
Agudelo-Hernández F, Vélez-Botero H, Delgado-Reyes AC.   +2 more
europepmc   +1 more source

Invitation : a human rights teach-in on trading away human rights? The role of the WTO

, 1999
Teach-in co-organized by International NGO Committee on Human Rights in Trade and Investment (INCHRITI). Affiliation taken from web site listed in flier. Affiliated web page url: www.pdhre.org. Clipped to three other PDHRE documents with the following
People's Decade for Human Rights Education (PDHRE)
core  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Contextualizing children's rights in sports: the impact of background and contextual factors on Swedish coaches' implementation of the UN convention on the rights of the child. [PDF]

Front Sports Act Living
Pavlogiannis G.
europepmc   +1 more source

Responsible Artificial Intelligence for Earth observation: human rights and the EU AI act. [PDF]

AI Ethics
Gevaert CM, Šćepanović S, Bernaz N, Taubenböck H, Kochupillai M.   +4 more
europepmc   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

A Health Rights Impact Assessment Guide for Artificial Intelligence Projects [PDF]

Health and Human Rights, 2020
Carmel Williams
doaj  

Legal consciousness revisited: a dynamic framework for rights awareness in a relational and mediated world. [PDF]

Front Sociol
Vargas Murillo AR, Falconi Tupiño HA.
europepmc   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Landscaping the early child care policy architecture in sub-Saharan Africa and an in-depth review of Kenya. [PDF]

Front Public Health
Nampijja M, Kitsao-Wekulo P, Oloo L, Muendo R, Owii H, Langat G.   +5 more
europepmc   +1 more source