Results 51 to 60 of about 2,226,607 (321)
Smaller is better: nanobodies meet NMR
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Dynamic Modeling and Simulation of a Rotating Single Link Flexible Robotic Manipulator Subject to Quick Stops [PDF]
Single link robotic manipulators are extensively used in industry and research operations. The main design requirement of such manipulators is to minimize link dynamic deflection and its active end vibrations, and obtain high position accuracy during its
Noroozi, Siamak, Dupac, Mihai
core +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
Dynamic modelling and control for fully-steerable large reflector antenna considering rigid-flexible coupling [PDF]
As the size of reflector antenna increases, the influence of flexible deformation to the system dynamics is much more significant. The coupling between the flexible deformation and the rigid displacement needs to be considered.
Congsi Wang +5 more
core +2 more sources
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source
Dynamic Simulation for Driver-Tricycle-Road System with Rigid-Flexible Coupling
Performance simulation for driver-tricycle-road hasn’t been reported currently. According to rigid-flexible coupling dynamic theory, this article took the frame and the spring as the spatial flexible body, used the UA tire model, considered the engine ...
Xiang Han
core +1 more source
Adenosine triphosphate as a modulator of protein interactions and stability
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley +1 more source
Coupling between flexible ship and liquid sloshing using potential flow analysis
The significant increase in demand for Liquefied Natural Gas (LNG) and the economic aspects of its transportation resulted in increases in the number and size of LNG carriers.
Temarel, Pandeli +3 more
core +2 more sources
Rigid-flexible coupling modeling of the dual-rotor system for aero-engine [PDF]
The dual-rotor system is the core component of advanced aero-engine. Establishing a reasonable, accurate, and efficient dynamics model is the key to studying the dynamics and vibration of the rotor system for aero-engine.
Dong, Yuehui +4 more
core +1 more source
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata +3 more
wiley +1 more source

