Results 61 to 70 of about 548,039 (242)
Jixie chuandong, 2013 According to the correlative knowledge of methods mechanics and calculus, the design equations for calculating the bending rigidity and stretching or compressing rigidity about the four kinds of composite flexural hinges are conducted. As an example, the
任宁, 耿铁, 周峰
doaj
Investigation of the fluctuation of the static axial rigidity for double-nut preloaded ball screws
Advances in Mechanical Engineering, 2019 This article aims to investigate the fluctuation of the static rigidity for preloaded ball screws. Based on the correlation between preload and friction torque, a new model to calculate the contact rigidity by friction torque is proposed.
Kai Wang, Chang-guang Zhou, Yi Ou
doaj +1 more source
Intercompartmental communication in senescence
FEBS Open Bio, EarlyView.Senescent cells experience structural changes in the plasma membrane, endoplasmic reticulum, mitochondria, lysosomes, nucleus, and cytoskeleton. These alterations disrupt crosstalk among cellular compartments, impairing vesicular trafficking, contact sites, and molecular flow.
Krystyna Mazan‐Mamczarz +3 more
wiley +1 more source
Aging and Cancer, EarlyView.Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
Cogwheel rigidity in Parkinson's disease: Clinical, biomechanical and neurophysiological features
Neurobiology of DiseaseObjectives: Cogwheel rigidity in Parkinson's disease has been poorly investigated so far, thus leaving the scientific interpretation of this phenomenon substantially unsolved.
Marco Falletti +4 more
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Rigidity of complete Riemannian manifolds with vanishing Bach tensor
, 2018 For complete Riemannian manifolds with vanishing Bach tensor and positive constant scalar curvature, we provide a rigidity theorem characterized by some pointwise inequalities. Furthermore, we prove some rigidity results under an inequality involving $L^{
Huang, Guangyue, Ma, Bingqing
core +1 more source
Network Localization of Fatigue in Multiple Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Fatigue is among the most common symptoms and one of the main factors determining the quality of life in multiple sclerosis (MS). However, the neurobiological mechanisms underlying fatigue are not fully understood. Here we studied lesion locations and their connections in individuals with MS, aiming to identify brain networks ...
Olli Likitalo +12 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela +13 more
wiley +1 more source
Chronological and Spatial Distribution of Skeletal Muscle Fat Replacement in FHL1‐Related Myopathies
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives Variants in the FHL1 gene cause FHL1‐related myopathies (FHL1‐RMs), a group of neuromuscular disorders with diverse clinical presentations. This study aimed to comprehensively characterize the spatial and temporal patterns of skeletal muscle fat replacement throughout the whole body in FHL1‐RMs, to examine disease progression over ...
Rui Shimazaki +8 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source