Results 91 to 100 of about 133,058 (212)

Molecular Engineering Boosts Photon‐Activated Immunotherapy for Prostate Cancer Through Concurrent Pyroptosis and cGAS‐STING Pathway Activation

open access: yesAngewandte Chemie, EarlyView.
The engineered DTSe‐based photosensitizer, DZTSe, emerges as an avant‐garde molecular entity, which can distribute to both the endoplasmic reticulum and mitochondria to concurrently trigger pyroptosis and activate the cGAS‐STING pathway. This dual‐action strategy effectively reprograms the tumor microenvironment, enabling potent eradication of primary ...
Cheng Zhang   +7 more
wiley   +2 more sources

Australia's Migration Strategy: An Effective Response to Migrant Worker Exploitation?

open access: yesAustralian Journal of Social Issues, EarlyView.
ABSTRACT A series of publicised migrant worker injuries and deaths has drawn attention to the issue of migrant worker exploitation (MWE) in Australia. In response, the Australian Government has included ‘Tackling Worker Exploitation’ as a key area of its Migration Strategy which it introduced in 2023. However, it is unclear how effective the Strategy’s
Evelyn Dowling, Alexandra Ridgway
wiley   +1 more source

Single‐Atom Control of Aromaticity and Excited‐State Dynamics in Endohedral Zirconium–Antimony Zintl Clusters

open access: yesAngewandte Chemie, EarlyView.
Single‐atom growth from [Zr@Sb12]2− to [Zr@Sb13]3− disrupts the closed‐shell S2P6 superatomic configuration and markedly attenuates three‐dimensional (3D) aromaticity. Ultrafast spectroscopy further links stronger spherical aromaticity to slower excited‐state relaxation, establishing an atom‐resolved structure‐aromaticity‐dynamics relationship ...
Yun Zhang   +7 more
wiley   +2 more sources

Intensified Manufactured Non‐Belonging: Working Holiday Makers in Australia During the COVID‐19 Pandemic

open access: yesAustralian Journal of Social Issues, EarlyView.
ABSTRACT Nations manufacture non‐belonging of temporary migrants through policy frameworks that produce exclusion. This precarity maximises the economic benefit of temporary migrant labour by minimising their political, social and legal rights. In this paper, we examine how non‐belonging targeting Working Holiday Makers (WHMs) is manufactured in ...
Donna James, Alanna Kamp
wiley   +1 more source

Iterative Synthesis of Pyrene–Coronene Molecular Graphene Nanoribbons

open access: yesAngewandte Chemie, EarlyView.
An iterative approach delivers a new family of undoped, cove‐edged graphene nanoribbons with lengths up to 9.1 nm that exhibit both molar absorptivity and fluorescence brightness values on the order of 105 M−1 cm−1 and an intrinsic charge‐carrier mobility of 475 ± 32 cm2 V−1 s−1.
Miguel A. Medel   +6 more
wiley   +2 more sources

Regional and Compartmental Changes Drive Progressive Patterns of Striatal Degeneration in X‐Linked Dystonia Parkinsonism

open access: yesAnnals of Neurology, EarlyView.
Objective Initially described in 1976, X‐linked dystonia parkinsonism (XDP) is a neurodegenerative disease that can be characterized by the presentation of dystonia and parkinsonism symptoms. Although this disease bears some resemblance to other neurodegenerative diseases in terms of symptomatology, the pathological signature of XDP is still unclear ...
Adelie Y.S. Tan   +19 more
wiley   +1 more source

Proteome‐Wide Target Identification Using Reactive Metallo‐Scaffolds (r‐mS): A Platform for Metallodrug Discovery

open access: yesAngewandte Chemie, EarlyView.
Re‐envisioning the Ligandable Proteome: Reactive Metallo‐Scaffolds (r‐mS) combine non‐covalent protein engagement by a metallo‐scaffold with covalent cysteine capture through a tethered chloroacetamide warhead. Chemoproteomic profiling reveals unique enzyme engagement including ligases, kinases and methyltransferases, highlighting opportunities for ...
Jessica E. Waters   +15 more
wiley   +2 more sources

Metacercárias livres (Digenea: Diplostomidae) em Rhinella fernandezae (Anura: Bufonidae) no Sul do Brasil Free metacercariae (Digenea, Diplostomidae) in Rhinella fernandezae (Anura: Bufonidae) in southern Brazil

open access: yesCiência Rural, 2009
Metacercárias livres de uma espécie não determinada de trematódeo digenético (Diplostomidae) foram encontradas nos rins de anuros da espécie Rhinella fernandezae coletados no Município de Imbé, Litoral Norte do Rio Grande do Sul, Brasil.
Viviane Gularte Tavares dos Santos   +1 more
doaj  

WCN24-2525 ANALYSIS OF THE IMPACT OF THE CORONAVIRUS PANDEMIC ON THE FOLLOW-UP OF POST KIDNEY TRANSPLANT PATIENTS IN A TRANSPLANT INSTITUTION IN SANTA CATARINA, BRAZIL

open access: yesKidney International Reports
Marina Abritta Hanauer   +5 more
doaj   +1 more source

Home - About - Disclaimer - Privacy