Results 91 to 100 of about 1,393,313 (319)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Research Communication: An International Tree-Ring Isotope Data Bank—A Proposed Repository For Tree-Ring Isotopic Data

open access: yes, 2009
The International Tree-Ring Data Bank (ITRDB) is an invaluable resource, providing access to a massive and growing cache of tree-ring data. Oxygen, carbon, nitrogen and hydrogen isotope treering studies, which have provided valuable climatic and ...
Csank, Adam Z.
core  

Aromatic Network: A Novel Structure for Power Distribution System

open access: yesIEEE Access, 2017
A distribution network is one of the main parts of a power system as it is connected directly to the load center and can act as a microgrid during an islanding operation.
F. R. Islam   +4 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

A Microcomputer-Based Tree-Ring Measuring System

open access: yes, 1980
A brief discussion is presented on a new measuring system based on an APPLE microcomputer. Aspects of both hardware and software are considered, with emphasis on the software that provides operator interaction.
Robinson, William J., Evans, Robert
core  

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Computer Assisted, Independent Observer Verification of Tree-Ring Measurements

open access: yes, 1997
The importance of tree-ring analyses to forestry and other disciplines (e.g., climate and ecology) requires that tree-ring measurements be as accurate as possible.
Grissino-Mayer, Henri D.
core  

CATATAN SINGKAT MENGENAI CINCIN BERTULISAN SRAMANA

open access: yesBerkala Arkeologi, 1983
Dalam tulisan singkat ini akan dibicarakan sebuah cincin yang menarik perhatian karena keunikan serta nilai kekunaannya. Keunikan cincin terletak pada tulisan berhuruf Jawa kuna di permukaannya yang berbunyi Sramana. Sampai saat ini sepanjang pengetahuan
Kusen Kusen
doaj   +1 more source

Commutative Rings whose Matrix Rings are Baer Rings [PDF]

open access: yesProceedings of the American Mathematical Society, 1969
A ring R with unit element is a Baer ring if every left annihilator in R has the form Re, where e is an idempotent element. K. G. Wolfson has proven [3, Corollary 15], that if R is a Priifer ring (a commutative integral domain in which every finitely generated ideal is invertible) then the ring of endomorphisms of a finitely generated free module over ...
openaire   +2 more sources

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

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