Results 91 to 100 of about 3,697,738 (296)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Radical Classes Closed Under Products
Analele Stiintifice ale Universitatii Ovidius Constanta: Seria Matematica, 2013 This is a survey of what is known about Kurosh-Amitsur radical classes which are closed under direct products. Associative rings, groups, abelian groups, abelian ℓ-groups and modules are treated.
Gardner Barry
doaj +1 more source
Modified spiral wound retaining ring [PDF]
, 1980 A spiral wound retaining ring with angled ends is described. The ring is crimped at the same angle as the ring ends to maintain a constant thickness dimension.
Lawson, A. G.
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Structure of anellovirus-like particles reveal a mechanism for immune evasion
Nature CommunicationsAnelloviruses are nonpathogenic viruses that comprise a major portion of the human virome. Despite being ubiquitous in the human population, anelloviruses (ANVs) remain poorly understood.
Shu-hao Liou +17 more
doaj +1 more source
Upper dimension and bases of zero-divisor graphs of commutative rings
AKCE International Journal of Graphs and Combinatorics, 2020 For a commutative ring with non-zero zero divisor set , the zero divisor graph of is with vertex set , where two distinct vertices and are adjacent if and only if .
S. Pirzada, M. Aijaz, S.P. Redmond
doaj +1 more source
Process development and fabrication of space station type aluminum-clad graphite epoxy struts [PDF]
The manufacture of aluminum-clad graphite epoxy struts, designed for application to the Space Station truss structure, is described. The strut requirements are identified, and the strut material selection rationale is discussed.
Ring, L. R.
core +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source