Results 171 to 180 of about 1,393,313 (319)

Southwest Archaeological Tree-Ring Dating

open access: yes, 1991
Final Report on NSF grant BNS-8504241 / 1 August 1985 - 31 July 1990 / Submitted to National Science Foundation Archaeometry ProgramNational Science Foundation Archaeometry Program / grant BNS-8504241.This item is part of the Natural History Reports ...
Dean, Jeffrey S.; Robinson, William J.
core  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Aegean Tree-Ring Signature Years Explained

open access: yes, 2001
As a long master tree -ring chronology for the region around the Aegean approaches completion, timbers from monuments and archaeological sites as far as 2,000 km apart, and as far back as 7000 BC, are being dated.
Latini, Christine   +5 more
core  

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Strategic Applications of Single-Atom Skeletal Editing in Natural Product Synthesis. [PDF]

open access: yesJ Am Chem Soc
Al-Ahmad R   +4 more
europepmc   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Ring, Randy 2. Interview about the Ring row house and Regatta races on Quidi Vidi Lake.

open access: yes, 2013
Ring discusses the history of rowing in the village with attention placed on his family’s experiences with the sport. In 1981 Ring, his father Skipper Jim Ring, and his brother Paul Ring were members of the Smith and Stockley Crew. During that year their
Morrison, Adrian
core  

Complex Adsorption Pattern Formation in Drying BSA-NaCl Droplets: Experimental Study. [PDF]

open access: yesInt J Mol Sci
Borshchegovskaya P   +9 more
europepmc   +1 more source

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