Results 91 to 100 of about 780,548 (303)

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

Analysis of Microstrip Line Fed Patch Antenna for Wireless Communications

Open Engineering, 2017
In this paper, theoretical analysis of microstrip line fed rectangular patch antenna loaded with parasitic element and split-ring resonator is presented.
Singh Ashish, Aneesh Mohammad, Kamakshi, Ansari J. A.   +3 more
doaj   +1 more source

Excitation Schemes of Plasmonic Angular Ring Resonator-Based Band-Pass Filters Using a MIM Waveguide

Photonics, 2019
This article describes the analysis and design of the excitation schemes of the plasmonic angular ring resonator-based band-pass filters using a metal-insulator-metal (MIM) waveguide.
Vishwanath Mittapalli, Habibulla Khan
doaj   +1 more source

Ring resonator based SOI biosensors [PDF]

, 2013
In this paper, two recent advances in silicon ring resonator biosensors are presented. First, we address the problem that due to the high index contrast, small deviations from perfect symmetry lift the degeneracy of the normal resonator mode.
Claes, T, Bienstman, Peter, J. Lammertyn, R. Puers, E. Hallynck, D. Martens, D. Witters, Lerma Arce, Cristina, Witters, D, Martens, Daan, C. Lerma Arce, Werquin, Sam, Puers, R, Hallynck, Elewout, Lammertyn, J, P. Bienstman, Hoste, Jan-Willem, S. Werquin, J.-W. Hoste, T. Claes   +19 more
core   +1 more source

Ofatumumab in Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease: A Comparison With Rituximab

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan, Lei Zhou, Jingzi ZhangBao, Hongmei Tan, Zhouzhou Wang, Chao Quan   +5 more
wiley   +1 more source

Air-coupled ultrasound detection using capillary-based optical ring resonators

Scientific Reports, 2017
We experimentally demonstrate and theoretically analyze high Q-factor (~107) capillary-based optical ring resonators for non-contact detection of air-coupled ultrasound. Noise equivalent pressures in air as low as 215 mPa/√Hz and 41 mPa/√Hz at 50 kHz and
Kyu Hyun Kim, Wei Luo, Cheng Zhang, Chao Tian, L. Jay Guo, Xueding Wang, Xudong Fan   +6 more
doaj   +1 more source

Miniaturized forced-mode ring resonator with capacitive loading

, 2012
The miniaturization of conventional ring resonators is demonstrated by forcing a voltage minimum at one end of the resonator. In addition, the resonator is loaded with a capacitance to achieve further miniaturization and reducing its sensitivity to ...
ALONSO CORONA CHAVEZ, JOSE LUIS OLVERA CERVANTES, JOSE ROBERTO REYES AYONA   +2 more
core  

Fabrication of tapered fiber based ring resonator

, 2010
Tapered fiber based ring resonators are fabricated and its optical characteristic is investigated in detail. The ring resonator is fabricated by coiling the tapered fiber, which is firstly made by heating and stretching a piece of optical fiber, after ...
Harun, Sulaiman Wadi, Ahmad, Harith, Jasim, A.A., Lim, K.S.   +3 more
core   +1 more source

Sex‐Stratified Association of Regional Dopamine Transporter Binding With Disease Progression in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To clarify the clinical relevance of dopamine transporter single‐photon emission computed tomography (DAT‐SPECT) abnormalities in amyotrophic lateral sclerosis (ALS), with a prespecified focus on sex‐stratified associations with disease progression and short‐term prognosis.
Tomoya Kawazoe, Keizo Sugaya, Kentaro Hayashi, Keiko Hino, Yasuhiro Nakata, Kota Bokuda, Toshio Shimizu, Kazushi Takahashi   +7 more
wiley   +1 more source

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers, Yaqiao Wei, Dinesh K. Deelchand, Adam Berrington, Young Woo Park, Guita Banan, Michal Povazan, Jens T. Rosenberg, André J. W. van der Kouwe, Tetsuo Ashizawa, Khalaf O. Bushara, Chiadi U. Onyike, Sub H. Subramony, Jeremy D. Schmahmann, Brian J. Soher, Peter B. Barker, Thomas H. Mareci, Eva‐Maria Ratai, Lynn E. Eberly, Gülin Öz   +19 more
wiley   +1 more source