Results 71 to 80 of about 2,048,259 (212)
The Journal of Physiology, EarlyView.Abstract figure legend Downregulation of mitotically associated long non‐coding RNA (MANCR) disturbs transcriptome and proteome in endothelial cells, possibly leading to endothelial and vascular dysfunction in preeclampsia. Abstract Preeclampsia (PE) is a hypertensive disorder during pregnancy, which is characterized by a wide spectrum of endothelial ...
Si‐Yan Zhang, Chi Zhou, Jing Zheng
wiley +1 more source
Pyridoxine‐sensitive X‐linked ‘sideroblastic’ anaemia in the absence of ring sideroblasts – molecular diagnosis [PDF]
British Journal of Haematology, 2017 No description ...
Thomas Creasey +5 more
openaire +3 more sources
Molecular Oncology, Volume 20, Issue 11, Page 2860-2875, November 2026.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, Volume 20, Issue 11, Page 2584-2610, November 2026.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Journal of Blood Medicine, 2020 Ghaith Abu-Zeinah, Maria T DeSancho Division of Hematology and Oncology, Department of Medicine, Weill Cornell Medicine, New York Presbyterian Hospital, New York, NY, USACorrespondence: Ghaith Abu-ZeinahWeill Cornell Medicine, New York Presbyterian ...
Abu-Zeinah G, DeSancho MT
doaj
HemaSphere, Volume 10, Issue 10, October 2026.Abstract Characterization of the presence and evolution of clonal hematopoiesis (CH) in patients with unexplained cytopenias is fundamental to risk‐stratifying patients and optimizing clinical surveillance for malignant progression. We investigated the mutational spectrum and clonal metrics in a cohort of 256 patients with chronic idiopathic ...
Grigorios Tsaknakis +11 more
wiley +1 more source
CRISPR/Cas9‐Mediated Correction of the SLC25A38 Mutation in a Patient With Sideroblastic Anemia
The Journal of Gene Medicine, Volume 28, Issue 10, October 2026.In this study, the identity of fibroblast cells isolated from the patient was identified using several methods. Then, the sgRNA3‐pX459 plasmid together with ssODN was transfected into fibroblast cells with a transfection efficiency of 49.64%. Finally, the entry of ssODN donor into fibroblast cells was confirmed using PCR‐RFLP and PAGE methods. ABSTRACT
Shokoufeh Yazdanparast +4 more
wiley +1 more source
, 2020 © 2020, Springer-Verlag London Ltd., part of Springer Nature. Myelodysplastic/myeloproliferative neoplasm with ring sideroblasts and thrombocytosis (MDS/MPN with RS-T), which exhibits both an increased number of marrow ring sideroblasts and ...
Hakimian, David +4 more
core +1 more source
Myelodysplastic syndrome: classification and changing concept
Journal of Pathology of Nepal, 2011 Myelodysplastic syndrome is a group of clonal disorders having wide range of outcome. Its classification and concept have been changed over time with better understanding of its prognosis and clinical significance.
A Ghosh
doaj +1 more source
British Journal of Haematology, Volume 209, Issue 4, Page 1469-1481, October 2026.Gene therapy is revolutionizing treatment paradigms for haemoglobinopathies, establishing a translational framework for disorders that impact red blood cell development. In their paper, Joshi et al. describe the preclinical and early clinical landscape of gene therapies for non‐haemoglobinopathy erythroid disorders and highlight common thematic ...
Gaurav Joshi +3 more
wiley +1 more source