Results 91 to 100 of about 15,241 (255)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

$W_1$-ELEMENTS IN A COMMUTATIVE RING WITH UNITY [PDF]

open access: yesInternational Journal of Pure and Apllied Mathematics, 2017
W. Nazeer   +3 more
openaire   +1 more source

Three Results for Non-Associative Semi Prime Ring with Unity. [PDF]

open access: yesInternational Journal of Advanced Research, 2016
B. SRIDEVI   +2 more
openaire   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Dual Notions of Prime Modules

open access: yesIbn Al-Haitham Journal for Pure and Applied Sciences, 2017
       Let R be a commutative ring with unity .M an R-Module. M is called coprime module     (dual notion of prime module) if ann M =ann M/N for every proper submodule N of M   In this paper we study coprime modules we give many basic properties of this
I. M. Ali, R. I. Khalaf
doaj  

Clique number and Chromatic number of a graph associated to a Commutative Ring with Unity

open access: yes, 2019
Let R be a commutative ring with unity (not necessarily finite). The ring R consider as a simple graph whose vertices are the elements of R with two distinct vertices x and y are adjacent if xy=0 in R, where 0 is the zero element of R. In 1988 [8], Beck raised the conjecture that the chromatic number and clique number are same in a graph associated to ...
openaire   +2 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Classical charge oscillations in nanoscopic systems

open access: yesRevista Brasileira de Ensino de Física
A single charge confined on the axis of a nanocylinder, carrying a charge of opposite sign, and two equal free classical charges on a conducting thin nanoring are two systems which can oscillate with frequencies in the THz domain.
R. De Luca, S. Ganci
doaj   +1 more source

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