Results 61 to 70 of about 15,584 (255)
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Some Extensions of Generalized Morphic Rings and EM-rings
Let R be a commutative ring with unity. The main objective of this article is to study the relationships between PP-rings, generalized morphic rings and EM-rings. Although PP-rings are included in the later rings, the converse is not in general true.
Ghanem Manal, Abu Osba Emad
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
To consider R is a commutative ring with unity, be a nonzero unitary left R-module, is known hollow module if each proper submodule of is small. L-hollow module is a strong form of hollow module, where an R-module is known L-hollow module if has
Thaer Z. Khlaif, Nada K. Abdullah
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The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Let R be a commutative ring with unity. In this paper we introduce the notion of chained fuzzy modules as a generalization of chained modules.
S. B. Semeein
doaj
Universal elements of unitriangular matrices groups
The following theorems are proved for a matrix g from the group of unitriangular matrices over a commutative and associative ring K of finite dimension of greater than three with unity: 1) if the matrix g is universal then all of its elements are on the
A.A. Konyrkhanova, N.G. Khisamiev
doaj +1 more source

