Results 41 to 50 of about 119,975 (244)
FEBS Open Bio, EarlyView.TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose +9 more
wiley +1 more source
FEBS Open Bio, EarlyView.IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli +3 more
wiley +1 more source
Selective elimination of quiescent cancer cells by dequalinium chloride via ROS‐mediated ferroptosis
FEBS Open Bio, EarlyView.Dequalinium chloride (DQ) selectively eliminates quiescent cancer cells (QCCs) by amplifying mitochondrial ROS. QCCs exhibit elevated basal ROS and limited redox‐buffering capacity, making them vulnerable to further ROS increases. DQ‐induced ROS exceeds the tolerance threshold, triggering lipid peroxidation and ferroptosis, whereas proliferating cells ...
Kotaro Miyamoto +14 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand +5 more
wiley +1 more source
Convolutional neural networks for Saimaa ringed seal segmentation [PDF]
, 2017 Nowadays, an automated photo-identification of animals is an emerging research topic due to appearance of large labor-intensive image datasets. The Saimaa ringed seal has a distinctive patterning of dark spots surrounded by light gray rings. This pattern
Kosyanenko, Evgeniya
core +1 more source
Comparative nasal and anal microbiomes in sympatric ringed and harbour seals: insights into host adaptation and niche differentiationComparative nasal and anal microbiomes in sympatric ringed and harbour seals: insights into host adaptation and niche differentiation [PDF]
Royal Society Open ScienceUnderstanding the microbiomes of marine mammals is essential to explore their health, ecological roles and responses to environmental change. We investigated the nasal and anal microbiota of two sympatric subarctic seals, the harbour seal (Phoca vitulina)
Carlos A. Domínguez-Sánchez +10 more
doaj +1 more source
Foraging ecology of ringed seals (Pusa hispida), beluga whales (Delphinapterus leucas) and narwhals (Monodon monoceros) in the Canadian High Arctic determined by stomach content and stable isotope analysis [PDF]
Polar Research, 2015 Stomach content and stable isotope analysis (δ13C and δ15N from liver and muscle) were used to identify habitat and seasonal prey selection by ringed seals (Pusa hispida; n=21), beluga whales (Delphinapterus leucas; n=13) and narwhals (Monodon monoceros;
Jordan K. Matley +2 more
doaj +1 more source
Advanced Engineering Materials, Volume 27, Issue 6, March 2025.ErB4 and NdB4 nanostructured powders are produced by mechanochemical synthesis. 5 h mechanical alloying and 4 M HCl acid leaching are used in the production. ErB4 and NdB4 powders exhibit maximum magnetization of 0.4726 emu g−1 accompanied with an antiferromagnetic‐to‐paramagnetic phase transition at about TN = 18 K and 0.132 emu g−1 with a maximum at ...
Burçak Boztemur +5 more
wiley +1 more source
, 2010 (Table 4) Mean numbers of parasites per ringed seal (Pusa hispida) collected from northwestern ...
Kit Maureen Kovacs (7998011) +9 more
core +1 more source