Results 131 to 140 of about 557,164 (317)

Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila

open access: yesFEBS Letters, EarlyView.
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia   +6 more
wiley   +1 more source

[News Clip: Rings recovered]

open access: yes, 1958
Video footage from the WBAP-TV station in Fort Worth, Texas to accompany a news story about the lost rings that were recovered. Mr. and Mrs.
WBAP-TV (Television station : Fort Worth, Tex.)
core  

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Units in Abelian Group Algebras Over Direct Products of Indecomposable Rings

open access: yesCubo, 2012
Let R be a commutative unitary ring of prime characteristic p which is a direct product of indecomposable subrings and let G be a multiplicative Abelian group such that G0/Gp is nite.
Peter Danchev
doaj  

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

A UNICORE based Multi Site and Multi User Grid Environment for Demonstration, Education and Testing Purposes

open access: yes, 2010
This article gives an overview of the novel Instant-Grid UNICORE edition. The Instant-Grid UNICORE edition allows to automatically set up a self-configured and independent multi site and multi user grid environment using the UNICORE 6 middleware.
Kálmán, Tibor, Rings, Thomas
core   +1 more source

On primitive ideals in graded rings

open access: yes, 2008
Let R = circle plus(infinity)(i=1) Ri be a graded nil ring. It is shown,that primitive ideals in R are homogeneous. Let A = circle plus(infinity)(i=1) Ai be a graded non-PI just-infinite dimensional algebra and let I be a prime ideal in A.
Smoktunowicz, Agata
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Ringed Spaces of Valuation Rings over Hilbert Rings

open access: yesTokyo Journal of Mathematics, 1995
Soit \((X, {\mathcal O}_X)\) un espace annelé, on lui associe l'espace annelé \((W, {\mathcal O}_W)\) où \(W\) est l'ensemble des points fermés de \(X\) et \({\mathcal O}_W\) la restriction de \({\mathcal O}_X\) à \(W\). Réciproquement, à un espace annelé \((W, {\mathcal O}_W)\) on associe l'espace annelé \(t(W, {\mathcal O}_W)\) de ses ensembles ...
openaire   +2 more sources

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