Results 171 to 180 of about 27,340 (267)
PharmVar GeneFocus: NAT2—Genetic Variation and Updated Nomenclature
Clinical Pharmacology &Therapeutics, EarlyView.The Pharmacogene Variation Consortium (PharmVar) provides nomenclature for the highly polymorphic human N‐acetyltransferase 2 (NAT2) gene. NAT2 metabolizes several clinically used drugs including isoniazid, hydralazine, amifampridine, procainamide, and sulfonamides such as dapsone, and also some highly carcinogenic arylamines.
Georgia Papanikolaou +14 more
wiley +1 more source
Da ECO-92 à RIO+20: uma breve avaliação de duas décadas
, 2012 Leandro Dias de Oliveira
openalex +2 more sources
Pharmacogenomics of Major Depressive Disorder in Indigenous Amazonian Populations
Clinical Pharmacology &Therapeutics, EarlyView.Major depressive disorder is a highly prevalent psychological disorder worldwide and its main treatment is the use of Selective Serotonin Reuptake Inhibitors. However, few studies have demonstrated the relationship between the presence of genetic variants in pharmacogenes and the efficacy of these drugs, especially in populations with a unique genetic ...
Kaio Evandro Cardoso Aguiar +9 more
wiley +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.Thiopurine methyltransferase (TPMT) and Nudix hydrolase 15 (NUDT15) are key enzymes that catabolize thiopurines. Decreased or no‐function alleles in TPMT and NUDT15 are associated with reduced or no enzyme activity and predictive of pronounced adverse effects, including severe myelosuppression, that may occur among individuals treated with standard ...
Maud Maillard +18 more
wiley +1 more source
National Identity Meaning and Attitudes Toward War, Peace, and the Future of Ukraine
Conflict Resolution Quarterly, EarlyView.ABSTRACT The link between attitudes and social identity is complex, influencing perceptions, motivations, and actions. Social psychological research mainly focused on the role of attitude in identity formation, particularly in the contexts of social movements and collective action.
Karina V. Korostelina +6 more
wiley +1 more source
Éditorial : Rio+20, dépasser l’horizon de la conférence
Développement Durable et Territoires, 2012 Helga-Jane Scarwell
doaj +1 more source
Informe i reflexions al voltant i després del PrepCom2 de la UNCSD 2012/RIO+20
, 2011 Xercavins, Josep
openalex +1 more source
Purpose and Profit: Social and Environmental Marketing for Large Companies in Adverse Scenarios
Corporate Social Responsibility and Environmental Management, EarlyView.ABSTRACT This qualitative study explored how large companies use social and environmental marketing to boost results in adverse scenarios, analyzing interviews with marketing managers and public documents. The findings reveal distinct strategies. To attract investors, environmental, social, and governance (ESG) communication is targeted at limited ...
Celso Jacubavicius +4 more
wiley +1 more source