Results 141 to 150 of about 49,586 (243)

Targeting WTAP/ROR1/WNT5A‐Mediated Crosstalk Between Glioma Stem Cells and Macrophages to Normalize Tumor Vasculature and Enhance Chemotherapy

Advanced Science, EarlyView.
In hypoxic microenvironment, WNT5A is predominantly secreted by tumor‐associated macrophages. Hypoxia‐induced WTAP mediates ROR1 stability by m6A modifications in a HuR‐dependent manner in Glioma stem cells (GSCs). WNT5A activates the WNT pathway via ROR1 binding on GSCs, driving glioma‐derived endothelial cells (GDECs) differentiation.
Xiaoyong Chen, Bo Pang, Yun Liu, Jiangwei Wang, Lanhui Zheng, Yuzhou Chang, Yingxuan Sun, Haoyuan Sun, Huiyuan Chen, Jiawei Cai, Zanyi Wu, Qing Chang, Yongzhi Wang, Dezhi Kang, Tao Jiang, Ruichao Chai   +15 more
wiley   +1 more source

Postoperative routine computed tomography allows detection of early-stage acute exacerbations of interstitial pneumonia. [PDF]

J Thorac Dis
Seto K, Ishikawa Y, Kimura K, Adachi T, Asakawa A, Kobayashi M, Ishibashi H, Tateishi U, Okubo K.   +8 more
europepmc   +1 more source

Asymmetric Cu─N─Ru Bridgedsite Nanozyme‐Loaded Injectable Thermogel Boosts Cuproptosis‐Like Death for Multidrug‐Resistant Urinary Tract Infections

Advanced Science, EarlyView.
To address multidrug‐resistant urinary tract infections (MDR‐UTIs), we developed Cu‐ZIF8‐Ru nanozyme featuring an asymmetric Cu─N─Ru catalytic site. This unique structure enhances multienzyme‐mimetic activity, eradicating resistant bacteria by inducing a cuproptosis‐like death pathway through intracellular Cu2+ accumulation and energy depletion.
Guanlin Li, Shike Zhang, Jinggong Liu, Xin Wang, Heng Wang, Hongcan Yang, Yuhao Zhou, Wen Liu, Hongxing Liu, Wenqi Wu   +9 more
wiley   +1 more source

Transmitter and ion channel profiles of saccadic omnipause neurons and cholinergic non-omnipause neurons in human nucleus raphe interpositus. [PDF]

Front Neuroanat
Mayadali ÜS, John M, Abspacher M, Schmitz C, Shaikh AG, Horn AKE.   +5 more
europepmc   +1 more source

Adhesion‐Related Macrophages Regulate Metabolic Homeostasis Through CAV‐1 Dependency

Advanced Science, EarlyView.
Adipose tissue harbors a distinct macrophage subpopulation, termed adhesion‐related macrophages (ARMs), which stably adhere to adipocytes. In obesity, ARMs represent the major expanding macrophage subset. They acquire material from adipocytes and rely on Caveolin‐1 for sustained lipid handling.
Wanyu Hu, Xiyan Liao, Limin Xie, Xiaoxiao Sun, Luodi Jing, Qin Zeng, Hongwei Jiang, Haowei Zhang, Lei Li, Fanqi Wang, Dandan Wang, Ying Mei, Yujin Din, Jianfeng Song, Wufuer Aini, Hui Zhou, Wanqin Xie, Helong Dai, Wei Liu, Joey Liu, Yan Cheng, Feng Liu, Willa A. Hsueh, Tuo Deng   +23 more
wiley   +1 more source

Collapsing Perisomatic Inhibition Leads to Epileptic Fast-Ripple Oscillations Caused by Pseudosynchronous Firing of CA3 Pyramidal Neurons. [PDF]

J Neurosci
Schlingloff D, Freund TF, Hangya B, Gulyás A.   +3 more
europepmc   +1 more source

Metarhizium anisopliae Mitigates the Phytotoxicity of Lead and Nanoplastics on Rice by Modifying Physiological, Transcriptomic, Metabolomic Activities, and Soil Microbiome

Advanced Science, EarlyView.
Metarhizium anisopliae alleviates the phytotoxic effects of polyethylene nanoplastics (NP) and lead (Pb) in rice by decreasing Pb uptake, restoring antioxidant and hormonal equilibrium, and promoting growth. Additionally, the fungus modifies the rhizosphere microbiota, enhancing both contaminant tolerance and plant growth, thereby effectively ...
Jing Peng, Qi Yan, Muhammad Umair Hassan, Muhammad Imran, Fasih Ullah Haider, Jianfeng Liang, Xingmin Wang, Shaukat Ali   +7 more
wiley   +1 more source

CARWL score as a predictor of radiation-induced periodontitis in locally advanced head and neck cancer undergoing concurrent chemoradiotherapy. [PDF]

Biomol Biomed
Bascil S, Somay E, Kılıc Durankuş N, Senyürek Ş, Ozturk D, Selek U, Topkan E.   +6 more
europepmc   +1 more source

Extracellular Vesicles in Autoimmune Diseases: From Diagnostic Biomarkers to Engineered Therapeutics

Advanced Science, EarlyView.
This review provides a systematic comparison of extracellular vesicles (EVs) from both mammalian and plant sources in the context of autoimmune diseases. It highlights their emerging roles as precision biomarkers and engineered therapeutic platforms.
Yufei Wu, Huiyuan Ma, Tinghui Zhu, Shuwei Huang, Manxi Lu, Qiong Wang, Zai‐Long Chi   +6 more
wiley   +1 more source

Exploring the Swimming and Water Safety Behaviour Among Indian and Vietnamese Adults in Australia. [PDF]

Health Promot J Austr
Low L, Graefe HLM, Willcox-Pidgeon SM, Barnett LM.   +3 more
europepmc   +1 more source