Results 241 to 250 of about 364,332 (362)

Catharina Stenqvist R.I.P.

open access: yesSvensk Teologisk Kvartalskrift, 2014
Gösta Hallonsten
doaj  

Caspase-8 and RIP kinases regulate bacteria-induced innate immune responses and cell death

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2014
D. Weng   +17 more
semanticscholar   +1 more source

The Evolutionarily Conserved TPM1 Super‐Enhancer Drives Skeletal Muscle Regeneration via Mechanotransduction Signaling

open access: yesAdvanced Science, EarlyView.
By integrating biomechanical and epigenetic cues, the evolutionarily conserved TPM1 super‐enhancer drives myogenesis via TEAD4‐mediated chromatin looping. This mechanism produces species‐specific outputs (linear TPM1 mRNA in mice and CircTPM1 in bovine) that activate PI3K/AKT mechanotransduction and the MYH10/MYL3 axis to execute cytoskeletal ...
Ruimen Zhang   +27 more
wiley   +1 more source

HuR Knockdown in MLO-Y4 Osteocyte-like Cells Elevates OPG Expression and Suppresses Osteoclastogenesis In Vitro. [PDF]

open access: yesInt J Mol Sci
Fan Z   +7 more
europepmc   +1 more source

RIP kinases: key decision makers in cell death and innate immunity

open access: yesCell Death and Differentiation, 2014
Fiachra Humphries   +4 more
semanticscholar   +1 more source

Targeting G3BP1 Condensate Topology Promotes Stress Granule Assembly via m6A‐IGF2BP1 for Ischemic Stroke Rescue

open access: yesAdvanced Science, EarlyView.
Our research reveals that small‐molecule icariin (ICA) directly binds Ras‐GTPase‐activating protein SH3 domain‐binding protein 1 (G3BP1), inducing conformational change and oligomerization. This interaction confers neuroprotection by recruiting insulin‐like growth factor 2 mRNA‐binding protein 1 (IGF2BP1) and modulating N6‐methyladenosine (m6A ...
Ling Li   +17 more
wiley   +1 more source

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