Results 31 to 40 of about 8,677 (293)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Crescimento de fungos na superfície de madeira de caixas do tipo 'K' usadas para hortaliças. [PDF]

open access: yes, 2016
A madeira é o material mais utilizado para embalagem de hortaliças noBrasil, principalmente devido ao seu baixo custo e alta resistênciamecânica. O objetivo deste trabalho foi estimar a absorção e a perdaprogressiva de água de ripas de madeira de Pinus ...
CALBO, A. G.   +2 more
core   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Pyriform Sinus Fistula

open access: yesPhilippine Journal of Otolaryngology Head and Neck Surgery, 2014
This 17-year-old young man attended the oromaxillofacial (OMF) department of a tertiary surgical center.  He had  attended both local and overseas ENT departments since the age of 5 years.  Previous, but unspecified surgery had been performed as a child,
Ian C. Bickle
doaj   +1 more source

Impact of Hypertension on Cognitive Decline and Dementia [PDF]

open access: yesAnnals of Geriatric Medicine and Research, 2020
Dementia reduces a person’s ability to perform their activities of daily living and is the leading cause of morbidity worldwide. While most preventive measures are ineffective in reducing dementia risk, active treatment of hypertension in middle-aged and
Han Lin Naing, Shyh Poh Teo
doaj   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Olfactory Neuroblastoma

open access: yesPhilippine Journal of Otolaryngology Head and Neck Surgery, 2016
This 57 year-old woman presented with a seizure. She had a history of attending the ENT and neurosurgical departments for more than a decade. At the time of her initial presentation many years prior, her main complaint was of nasal congestion.
Ian C. Bickle
doaj   +1 more source

Sistema Intensivo de Suínos Criados ao Ar Livre - SISCAL: comedouro de creche. [PDF]

open access: yes, 2015
bitstream/item/58320/1/CUsersPiazzonDocuments282 ...
COLOMBO, S.   +4 more
core   +1 more source

Compressão de tomate (Lycopersicon esculentum P. Miller) em função do fechamento da caixa de madeira tipo "K" [PDF]

open access: yes, 2010
Wood boxes kind "k" are the most used in table tomato (Lycopersicon esculentum P. Miller) commercialization in Brazil. Due to the fruit accommodation process that occurs during the transport from the production place to the commercialization point ...
CALBO, Adonai Gimenez   +2 more
core   +3 more sources

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