Results 71 to 80 of about 15,419,997 (324)

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

An Economic Ripple Effect Analysis of Domestic Supercomputing Simulation in the Industrial Sector

Journal of Information Science Theory and Practice, 2022
The manufacturing industry is the foundation that drives economic growth, and manufacturing innovation is essential for sustainable growth advantage and the transition into a digital economy.
Mihyun Ko, Myungil Kim, Sung-Uk Park
doaj   +1 more source

Ripple oscillations in the left temporal neocortex are associated with impaired verbal episodic memory encoding

, 2018
Background: We sought to determine if ripple oscillations (80-120Hz), detected in intracranial EEG (iEEG) recordings of epilepsy patients, correlate with an enhancement or disruption of verbal episodic memory encoding.
Berry, Brent, Camarillo-Rodriguez, Liliana, Chervenova, Inna, Das, Sandhitsu, Davis, Katheryn A., Davis, Leon A., Elahian, Bahareh, Ganne, Chaitanya, Gorniak, Richard, Gross, Robert, He, Xiao-Song, Inman, Cory S., Jobst, Barbara C., Khadjevand, Mehraneh, Kucewicz, Michal, Lega, Bradley C., Rizzuto, Daniel S., Sharan, Ashwini D., Shimamoto, Shoichi, Sperling, Michael, Stein, Joel, Tracy, Joseph, Waldman, Zachary J., Wanda, Paul, Weiss, Shennan A., Worrell, Gregory, Zaghloul, Kareem   +26 more
core   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Ripple Effect: The Economic Impact of Microlending [PDF]

, 2010
Examines the direct, indirect, and induced economic effects of the Opportunity Fund's microfinance lending on the Bay Area in terms of economic activity, employee earnings, employment, and tax revenue.

core  

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Direct observation of ion-induced self-organization and ripple propagation processes in atomistic simulations

Materials Research Letters, 2020
Patterns on sand generated by blowing winds are one of the most commonly seen phenomena driven by such a self-organization process, as has been observed at the nanoscale after ion irradiation. The origins of this effect have been under debate for decades.
A. Lopez-Cazalilla, F. Djurabekova, A. Ilinov, C. Fridlund, K. Nordlund   +4 more
doaj   +1 more source

Is there a ripple effect in environmental regulation in China? – Evidence from the local-neighborhood green technology innovation perspective

, 2020
Environmental regulation and green technology progress are important means to solve the negative externalities of the environmental pollution. Despite the widespread concern on the impact of environmental regulation on green technology progress, the ...
Zhiqing Dong, Yongda He, Hui Wang, Lin-Hui Wang   +3 more
semanticscholar   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Analytical method for designing grating compensated dispersion-managed soliton systems [PDF]

, 2004
This paper was published in Journal of Optical Society of America B and is made available as an electronic reprint with the permission of OSA. The paper can be found at the following URL on the OSA website: http://www.opticsinfobase.org/abstract.cfm?URI ...
Kaliyaperumal, Nakkeeran, Kwan, Y. H. C., Wai, P. K. A.   +2 more
core   +1 more source