Results 141 to 150 of about 81,703 (295)

Iflaviruses in arthropods: when small is mighty

open access: yesInsect Science, EarlyView.
Many arthropod species harbor iflaviruses, which often cause covert (asymptomatic) infections, but may still affect host fitness. We review the impact of iflaviruses on arthropod fitness, immunity, behaviour as well as the iflavirus’ host range, transmission, tissue tropism and the interactions with other microorganisms within arthropods.
Annamaria Mattia   +3 more
wiley   +1 more source

Mapping PTSD across the symptom spectrum: Affective, emotion regulation and cumulative trauma predictors in Syrian refugees: A quantile regression approach

open access: yesBritish Journal of Clinical Psychology, EarlyView.
Abstract Objectives This study examined whether affective factors, emotion regulation strategies, cumulative trauma exposure, resilience and perceived social support are differentially associated with PTSD symptom severity across the symptom spectrum in Syrian refugees. Design Cross‐sectional study.
Emre Han Alpay
wiley   +1 more source

Long non‐coding RNAs at the crossroads of inflammation, cancer and angiogenesis: Molecular mechanisms and their potential as therapeutic targets

open access: yesBritish Journal of Pharmacology, EarlyView.
Long non‐coding RNAs (lncRNAs), a broad class of non‐protein‐coding RNAs, are characterized as new regulators of gene expression at the epigenetic, transcriptional, and post‐transcriptional level. Thus, lncRNAs are involved in the regulation of physiological processes and the development of human diseases and cancer by modulating proinflammatory ...
Charlie Leboff   +3 more
wiley   +1 more source

The Predictive Power of Socio‐Economically Disadvantaged Children's Problem Solving Skills and Their Mothers' Parental Attitudes on Theirs Resilience Levels

open access: yesChild &Family Social Work, EarlyView.
ABSTRACT This study aimed to examine the predictive power of problem‐solving skills and maternal parenting attitudes on the resilience levels of 5‐year‐old children living in socio‐economically disadvantaged communities. The study sample consisted of 208 five‐year‐old children attending independent kindergartens affiliated with the Ministry of National
Sümeyye Safali Turan   +1 more
wiley   +1 more source

Exploratory Study on the Potential Moderating Effects of Protective and Risk Factors on the Negative Impact of Parental Stress on Family Quality of Life in Parents of Children With Autism (CLWA)

open access: yesChild &Family Social Work, EarlyView.
ABSTRACT Chinese caregivers of autistic children report heightened parental stress, which in turn can negatively influence their family quality of life (FQoL). To better support the quality of life of Chinese caregivers of autistic children, the present study investigated the relationship between parental stress and FQoL and the moderating roles of ...
Wing‐Chee So   +4 more
wiley   +1 more source

Challenges in Gene‐Directed Therapies for Rare Neurodevelopmental Disorders Using HNRNPU as an Exemplar

open access: yesClinical Genetics, EarlyView.
Beyond diagnosing rare neurodevelopmental disorders like HNRNPU‐RNDD, developing gene‐directed therapies requires overcoming complex hurdles, including spatial, developmental, and cell‐type constraints. Addressing these requires understanding the molecular effects of dosage and chromatin dynamics to deliver precise, effective treatments.
Daniel Aiyedun   +3 more
wiley   +1 more source

Real‐World Treatment Patterns and Weight Outcomes Before and After a Tirzepatide Price Increase in Over One Million Self‐Paying UK Adults With Overweight or Obesity

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Glucagon‐like peptide‐1 (GLP‐1) receptor agonist‐based medicines are highly effective treatments for overweight and obesity, but population‐scale real‐world evidence remains limited, particularly in self‐funded settings where treatment choice may be influenced by relative price.
Sophie Dix   +7 more
wiley   +1 more source

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