Results 211 to 220 of about 14,369,089 (255)

Risk factors for central lymph node metastasis in papillary thyroid microcarcinoma: a simplified risk scoring system. [PDF]

Front Endocrinol (Lausanne)
Liu S, Zhang J.
europepmc   +1 more source

Metabolic and Fluid Biomarkers Support Microglia Activation in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Amyotrophic lateral sclerosis is an incurable neurodegenerative disease involving motor neuron degeneration and metabolic and immune dysfunction. We combined clinical data, cerebrospinal fluid biomarkers and fluorodeoxyglucose positron emission tomography with magnetic resonance imaging to investigate the role of reactive microglia in disease ...
Matteo Zanovello, Francesca Serani, Alen Bebeti, Federica Paredi, Giulia Quadrio, Andrea Fortuna, Giacomo Maria Minicuci, Elena Pegoraro, Annachiara Cagnin, Diego Cecchin, Gianni Sorarù   +10 more
wiley   +1 more source

Severe infections, domain-specific cognitive vulnerability, and future infection risk in older adults. [PDF]

Brain Behav Immun Health
Gao Y, Kivimäki M, Frank P, Scholes S, Zaninotto P, Steptoe A.   +5 more
europepmc   +1 more source

Association Between Neurofilament Light Chain and Real‐World Ambulatory Function in Progressive MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurofilament light chain (NfL) is a biomarker of neuroaxonal injury in multiple sclerosis (MS), yet associations with functional outcomes remain unclear. Longitudinal associations between serum NfL (sNfL) and daily step count (STEPS) from wearable devices were assessed in a large international progressive MS cohort.
Gabby B. Joseph, Megan McCune, Riley Bove, Ahmed Abdelhak, Bruce A. C. Cree, Valerie J. Block   +5 more
wiley   +1 more source

Frailty, Physical Performance, and Molecular Changes in Older Adults Participating in Different Exercise Programs: A 12-Week Preference-Based Non-Randomized Study. [PDF]

Nutrients
Li J, Yang H, Zhen H, Li Z, Lu J, Yan H, Nie C, Lu Y.   +7 more
europepmc   +1 more source

Clinical Impact of MGMT Promoter Methylation in IDH‐Mutant Gliomas: Influence of Threshold Selection and Clinical Confounding

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background The clinical relevance of MGMT promoter methylation in IDH‐mutant gliomas remains controversial in the era of molecular classification. We aimed to systematically evaluate its clinical relevance by integrating quantitative assessment, cutoff exploration, and adjustment for clinical confounding.
Haihui Jiang, Linxi Cao, Xiaodong Chen, Siqi Tong, Qinghui Zhu, Jun Yang, Song Lin, Yong Cui   +7 more
wiley   +1 more source

Machine Learning Prediction and Causal Forest Analysis of Severe Acute Kidney Injury in ICU Patients with COPD: A MIMIC-IV Study. [PDF]

Int J Chron Obstruct Pulmon Dis
Fang L, Wang F, Chen J, Zheng Y.
europepmc   +1 more source

Subjective Cognitive Concerns and Cognitive Trajectories in Parkinson's Disease: Biomarker Impact

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the relationship of subjective cognitive concerns (SCC) with biomarkers of Alzheimer's disease (AD), neurodegeneration, and Parkinson's disease (PD) and domain‐specific cognitive trajectories among cognitively unimpaired persons with de novo PD. Method Cognitively unimpaired participants with SCC (n = 294) and without SCC (
Francesca V. Lopez, Fareshte Erani, Katherine J. Bangen, David G. Coughlin, Douglas Galasko, Kelsey R. Thomas   +5 more
wiley   +1 more source

Incident Falls Across Concordant and Discordant Profiles of Concerns About Falling and Functional Mobility in Older Adults: A Prospective Cohort Study. [PDF]

Clin Interv Aging
Fei F, Zhong J, Guo L, You L, Zhao M.
europepmc   +1 more source