Results 131 to 140 of about 6,585,193 (310)

Bank insolvency risk and aggregate Z-score measures: a caveat [PDF]

open access: yes
We demonstrate that a popular approach to constructing (weighted) mean-based aggregate bank insolvency risk measures is inherently biased; we also suggest an alternative approach that avoids this problem.insolvency risk, aggregate Z-score, Jensen's ...
Frank Strobel
core  

Credit risk with semimartingales and risk-neutrality [PDF]

open access: yes, 2008
A no-arbitrage framework to model interest rates with credit risk, based on the LIBOR additive process, and an approach to price corporate bonds in incomplete markets, is presented in this paper.
Colino, Jesús P., Stute, Winfried
core   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

A generalized risk approach to path inference based on hidden Markov models

open access: yes, 2012
Motivated by the unceasing interest in hidden Markov models (HMMs), this paper re-examines hidden path inference in these models, using primarily a risk-based framework. While the most common maximum a posteriori (MAP), or Viterbi, path estimator and the
Koloydenko, Alexey A., Lember, Jüri
core  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

A Risk-Based Approach in Rehabilitation of Water Distribution Networks. [PDF]

open access: yesInt J Environ Res Public Health, 2022
Raspati GS   +5 more
europepmc   +1 more source

The development of the portfolio management for the unit investment funds [PDF]

open access: yes
The paper analyses common Russian practice of assessment of the effectiveness of the unit investment fund portfolio management based on the risk/return tradeoff. The paper identifies characteristics, advantages and disadvantages of various portfolio risk
Nikiforova, Vera, Sergeeva, Irina
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Risk-based approach to choosing the production asset management strategy for energy company

open access: yesИзвестия высших учебных заведений: Проблемы энергетики
RELEVANCE: The possibility of a reasonable choice of an alternative strategy for the organization of maintenance and repair (M&R) of the power company's equipment is a guarantee of the successful implementation of its strategic priorities.
V. M. Levin   +2 more
doaj   +1 more source

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