Results 231 to 240 of about 34,840,596 (291)

Dimethyl Fumarate, But Not Rituximab, Reduces Serum GFAP Levels and PIRMA in Relapsing–Remitting MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Serum neurofilament light chain (sNfL) and glial fibrillary acidic protein (sGFAP) levels are believed to reflect mainly acute and chronic disease processes in multiple sclerosis (MS), respectively. In this study, we investigated whether dimethyl fumarate (DMF) and rituximab (RTX) differentially affect these biomarkers.
F. Shawket, J. Lycke, J. Salzer, F. Piehl, K. Fink, N. Lange, J. Mellergård, C. Malmeström, P. Sundström, I. Erngren, A. al‐Grety, E. Freyhult, K. Kultima, J. Burman, A. Svenningsson   +14 more
wiley   +1 more source

Memory and Resting‐State Connectivity in Acute Transient Global Amnesia: A Case–Control fMRI Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Transient global amnesia (TGA) is a striking model of isolated amnesia. While hippocampal lesions are well described, the network‐level mechanisms and the precise neuropsychological profile remain debated. Our objective was thus to characterize functional and neuropsychological correlates of acute TGA and their ...
Elias El Otmani, Emmanuel Barbeau, Béatrice Lemesle, Emilie Milongo‐Rigal, Sophie Fernandez, Sandrine Charpentier, Jean‐François Albucher, Nicolas Raposo, Fabrice Bonneville, Patrice Péran, Jérémie Pariente   +10 more
wiley   +1 more source

Comprehensive Assessment of Arterial, Tissue, and Venous Collaterals for Evaluating the Infarct Growth Rate: The Multimodal Collateral Score

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Collaterals are crucial factors that influence the infarct growth rate (IGR). We aimed to determine whether a comprehensive multimodal collateral score (MCS), incorporating collateral assessment at the arterial, tissue, and venous levels, is associated with functional independence and provides incremental prognostic value over ...
Giorgio Busto, Umberto Pensato, Ilaria Casetta, Giorgio U. Marcello, Angelo Barra, Anna Poggesi, Edoardo Carlesi, Sara Mancini, Andrea Ginestroni, Vittorio Miele, Alessandro Padovani, Andrea Morotti, Enrico Fainardi   +12 more
wiley   +1 more source

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Issues of the Risk-Based Approach

Issues of Risk Analysis, 2022
The purpose of the article was to analyze the problems currently standing in the way of more effective application of the risk-based approach methodology in the field of technogenic safety management. Methods — theoretical, inductive method, analysis of own experience, adopted normative legal acts, other publications.
E. Yu. Kolesnikov, F. Vasileios
openaire   +1 more source

A Risk-Based Approach to Penicillin Allergy

Immunology and Allergy Clinics of North America, 2022
Penicillin allergy can be risk stratified in the hospital or outpatient setting to identify low-, moderate-, and high-risk phenotypes. Following ascertainment of risk, dedicated penicillin allergy testing strategies can be deployed successfully for each risk type-direct oral challenge (low risk), skin testing and oral challenge (moderate risk), and ...
openaire   +2 more sources

The Risk-Based Approach to Data Protection

2020
Abstract The main goal of this book is to provide an understanding of what is commonly referred to as “the risk-based approach to data protection”. An expression that came to the fore during the overhaul process of the EU’s General Data Protection Regulation (GDPR)—even though it can also be found in other statutes under different ...
openaire   +4 more sources

A dynamic risk-based approach to managing a pandemic

Journal of Business Continuity & Emergency Planning, 2021
A pandemic is a unique natural disaster that will pose challenges for any organisation. During the COVID-19 pandemic, for example, organisations of all types have struggled to maintain operations while assuring the health and wellbeing of the various persons who work on their behalf.
openaire   +2 more sources

Menopause management: a cardiovascular risk-based approach

Climacteric, 2009
Hormone replacement therapy (HRT) remains the gold standard for the management of menopausal symptoms; however, HRT use has declined due to concerns over possible adverse side-effects. Approaches to menopause management are continually being revised and these extend beyond the control of recognized menopausal symptoms to encompass wider aspects of ...
C J, Haines, E, Farrell
openaire   +2 more sources

The risk-based approach in practice

2020
Abstract The goal of this chapter is to analyse some of the main caveats associated with the risk-based approach in practice, that is, with the use of meta regulation. The risk-based approach is an attempt to address some of the issues that data protection as command and control regulation has faced.
openaire   +1 more source