Results 81 to 90 of about 5,018,421 (303)

Risk sharing in the small and in the large [PDF]

open access: yesJournal of Economic Theory, 2018
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Paolo Ghirardato   +1 more
openaire   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Risk-sharing and its role in manufacturer’s innovation

open access: yesProduction and Manufacturing Research: An Open Access Journal
This study seeks a more developed understanding of the nature of manufacturers’ risk-sharing relations with suppliers and customers and how these relations and the use of manufacturing technologies affect process and product innovation.
Gregory Theyel, Christopher Tucci
doaj   +1 more source

Coalitions, Incentives, and Risk Sharing [PDF]

open access: yesJournal of Economic Theory, 1993
The paper investigates the possibility that in a principal agent problem it may be preferable, from the standpoint of the principal, to have cooperative rather than non-cooperative behaviour on the part of the agents. \(P_{ij}(e_ 1,e_ 2)\) denotes the joint probability of the (stochastic) output pair \((x^ 1_ i,x^ 2_ j)\) being realized when effort ...
openaire   +2 more sources

Taxes and International Risk Sharing [PDF]

open access: yesSSRN Electronic Journal, 2014
We examine the extent to which differences in international tax rates may account for the small correlations of per capita consumption fluctuations across countries. Theory implies a close relationship between relative consumption growth, and consumption and capital income tax rate differentials. We find strong empirical evidence for this relationship.
Epstein, Brendan   +2 more
openaire   +2 more sources

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

West African Monetary Integration and Interstates Risk-Sharing [PDF]

open access: yes
There are continuing efforts at the monetary integration and unionization in West Africa. Several academics argue that a monetary union among West African states would be costly because of the magnitude of asymmetric shocks.
Sampawende Jules Tapsoba
core   +2 more sources

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Modeling Risk Sharing and Impact on Systemic Risk

open access: yesMathematics
This paper develops a simplified agent-based model to investigate the dynamics of risk transfer and its implications for systemic risk within financial networks, focusing specifically on credit default swaps (CDSs) as instruments of risk allocation among
Walter Farkas, Patrick Lucescu
doaj   +1 more source

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