Results 171 to 180 of about 23,955,491 (386)
Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single‐cell RNA sequencing analysis
Molecular Oncology, EarlyView.Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.Sungyeon Kim, Myunghee Kang, Soyeon Jeong, Jisup Kim, Kyoung Oh Kim, Won‐Suk Lee, Jeong‐Heum Baek, Jung Ho Kim, Seungyoon Nam +8 morewiley +1 more sourceHighly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors
Molecular Oncology, EarlyView.Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi +10 morewiley +1 more sourceExploration of heterogeneity and recurrence signatures in hepatocellular carcinoma
Molecular Oncology, EarlyView.This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.Wen‐Jing Wu, Jianchao Wang, Fuqing Chen, Xuefeng Wang, Bin Lan, Ruyi Fu, Hong Wen, Fangfang Chen, Wei Hong, Tian‐Yu Tang, Ying He, Gang Chen, Jianyin Zhou, Hai‐Long Piao, Di Chen, Shu‐Yong Lin +15 morewiley +1 more sourceGlobal, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015
The Lancet, 2016 M. Forouzanfar, A. Afshin, Lily T Alexander, H. R. Anderson, Z. Bhutta, S. Biryukov, M. Brauer, R. Burnett, Kelly M. Cercy, F. Charlson, A. Cohen, L. Dandona, Kara Estep, A. Ferrari, J. Frostad, N. Fullman, P. Gething, W. Godwin, Max G Griswold, Simon Iain Hay, Y. Kinfu, H. Kyu, H. Larson, Xiaofeng Liang, Stephen S. Lim, Patrick Y. Liu, Alan D. Lopez, R. Lozano, L. Marczak, G. Mensah, A. Mokdad, M. Moradi-Lakeh, M. Naghavi, B. Neal, M. Reitsma, Gregory A. Roth, J. Salomon, P. Sur, T. Vos, Joseph A Wagner, Haidong Wang, Yi Zhao, Maigeng Zhou, Gunn Marit Aasvang, A. Abajobir, K. H. Abate, C. Abbafati, K. Abbas, F. Abd-Allah, A. Abdulle, S. Abera, Biju Abraham, L. Abu-Raddad, G. Abyu, A. Adebiyi, I. Adedeji, Z. Ademi, A. K. Adou, J. Adsuar, E. Agardh, A. Agarwal, Anurag Agrawal, A. Kiadaliri, O. Ajala, T. Akinyemiju, Z. Al-Aly, K. Alam, N. Alam, S. Aldhahri, R. Aldridge, Z. A. Alemu, R. Ali, A. Alkerwi, F. Alla, P. Allebeck, U. Alsharif, K. Altirkawi, E. A. Martin, N. Alvis-Guzmán, Azmeraw T. Amare, A. Amberbir, A. Amegah, H. Amini, W. Ammar, S. Amrock, H. Andersen, B. Anderson, C. Antonio, P. Anwari, J. Ärnlöv, A. Artaman, H. Asayesh, R. Asghar, Reza Assadi, S. Atique, Euripide Avokpaho, A. Awasthi, B. Quintanilla, P. Azzopardi, U. Bacha, A. Badawi, M. Bahit, K. Balakrishnan, A. Barać, Ryan Barber, S. Barker-Collo, T. Bärnighausen, S. Barquera, L. Barregard, L. Barrero, S. Basu, C. Batis, S. Bazargan-Hejazi, J. Beardsley, Neeraj Bedi, E. Beghi, B. Bell, M. Bell, A. Bello, D. Bennett, I. Benseñor, A. Berhane, E. Bernabé, B. Betsu, A. Beyene, N. Bhala, A. Bhansali, S. Bhatt, S. Biadgilign, B. Bikbov, D. Bisanzio, E. Bjertness, J. Blore, R. Borschmann, S. Boufous, R. Bourne, M. Brainin, A. Brazinova, N. Breitborde, H. Brenner, D. Broday, T. Brugha, B. Brunekreef, Z. Butt, L. Cahill, Bianca Calabria, Ismael Campos-Nonato, Rosario Cárdenas, D. Carpenter, J. Carrero, Daniel C. Casey, C. Castañeda-Orjuela, Jacqueline Castillo Rivas, R. Castro, F. Catalá-López, Jung-Chen Chang, P. Chiang, Mirriam Chibalabala, Odgerel Chimed-Ochir, V. Chisumpa, Abdulaal Chitheer, J. Choi, H. Christensen, D. Christopher, Liliana G. Ciobanu, M. Coates, Samantha M. Colquhoun, A. C. Manzano, Leslie T. Cooper, Kimberly Cooperrider, Leslie Cornaby, Monica Cortinovis, J. Crump, L. Cuevas-Nasu, A. Damasceno, R. Dandona, S. Darby, P. Dargan, J. D. das Neves, A. Davis, K. Davletov, E. F. de Castro, Vanessa De la Cruz-Góngora, D. de Leo, L. Degenhardt, Liana C. Del Gobbo, B. del Pozo-Cruz, R. Dellavalle, A. Deribew, D. Jarlais, S. Dharmaratne, P. Dhillon, C. Díaz-Torné, D. Dicker, E. Ding, E. Dorsey, Kerrie E. Doyle, T. Driscoll, L. Duan, M. Dubey, B. Duncan, I. Elyazar, A. Endries, S. Ermakov, H. Erskine, B. Eshrati, A. Esteghamati, S. Fahimi, E. J. Faraon, T. Farid, C. Farinha, Andre Faro, M. Farvid, F. Farzadfar, V. Feigin, S. Fereshtehnejad, J. Fernandes, F. Fischer, J. Fitchett, T. Fleming, N. Foigt, Kyle Foreman, F. Fowkes, R. Franklin, Thomas Fürst, N. Futran, E. Gakidou, A. García-Basteiro, T. Gebrehiwot, A. Gebremedhin, J. Geleijnse, B. Gessner, A. Z. Giref, M. Giroud, Melkamu Dedefo Gishu, G. Giussani, S. Goenka, M. Gómez-Cabrera, H. Gómez-Dantés, P. Gona, A. Goodridge, S. Gopalani, C. Gotay, A. Goto, H. Gouda, H. Gugnani, F. Guillemin, Yuming Guo, Rahul Gupta, Rajeev Gupta, R. A. Gutiérrez, J. Haagsma, N. Hafezi-Nejad, D. Haile, G. B. Hailu, Y. Halasa, R. Hamadeh, S. Hamidi, A. Handal, G. Hankey, Y. Hao, H. Harb, S. Harikrishnan, J. Haro, Mohammad Sadegh Hassanvand, T. A. Hassen, Rasmus J Havmoeller, I. Heredia-Pi, N. Hernández-Llanes, P. Heydarpour, H. Hoek, H. Hoffman, M. Horino, N. Horita, H. Hosgood, D. Hoy, M. Hsairi, A. Htet, G. Hu, John J Emmanuel Huang, A. Husseini, S. Hutchings, I. Huybrechts, K. Iburg, B. Idrisov, B. Ileanu, M. Inoue, T. Jacobs, K. Jacobsen, N. Jahanmehr, M. Jakovljevic, H. Jansen, S. Jassal, Mehdi Javanbakht, S. Jayaraman, A. Jayatilleke, S. Jee, P. Jeemon, V. Jha, Ying Jiang, T. Jibat, Ye Jin, C. Johnson, J. Jonas, Z. Kabir, Y. Kalkonde, R. Kamal, H. Kan, A. Karch, C. Karema, C. Karimkhani, A. Kasaeian, Anil Kaul, N. Kawakami, Dhruv S. Kazi, P. Keiyoro, L. Kemmer, A. Kemp, A. Kengne, A. Keren, C. Kesavachandran, Y. Khader, Abdur Rahman Khan, E. Khan, G. Khan, Y. Khang, S. Khatibzadeh, S. Khera, T. Khoja, J. Khubchandani, C. Kieling, Cho-il Kim, Daniel H. Kim, R. Kimokoti, N. Kissoon, M. Kivipelto, L. Knibbs, Y. Kokubo, J. Kopec, P. Koul, A. Koyanagi, M. Kravchenko, H. Kromhout, H. Krueger, Tiffany Ku, B. K. Defo, R. Kuchenbecker, B. K. Bicer, E. Kuipers, G. Kumar, G. Kwan, D. Lal, R. Lalloo, T. Lallukka, Q. Lan, A. Larsson, A. Latif, A. Lawrynowicz, J. Leasher, J. Leigh, J. Leung, M. Levi, Xiaohong Li, Yichong Li, Juan Liang, Shiwei Liu, B. Lloyd, G. Logroscino, P. Lotufo, R. Lunevicius, Michael F. MacIntyre, M. Mahdavi, M. Majdan, A. Majeed, R. Malekzadeh, D. Malta, Wondimu Ayele Ayele Manamo, C. Mapoma, W. Marcenes, R. Martin, J. Martínez-Raga, F. Masiye, K. Matsushita, R. Matzopoulos, B. Mayosi, J. Mcgrath, M. Mckee, P. Meaney, C. Medina, A. Mehari, Fabiola Mejía-Rodríguez, A. Mekonnen, Y. Melaku, Z. Memish, W. Mendoza, Gert B. M. Mensink, A. Meretoja, T. Meretoja, Y. Mesfin, F. Mhimbira, Anoushka I Millear, T. Miller, E. Mills, M. Mirarefin, Awoke Misganaw, C. Mock, A. Mohammadi, S. Mohammed, G. Mola, L. Monasta, J. M. Hernandez, M. Montico, L. Morawska, R. Mori, D. Mozaffarian, U. Mueller, Erin C. Mullany, J. Mumford, G. Murthy, J. Nachega, A. Naheed, V. Nangia, N. Nassiri, J. Newton, Marie Ng, Q. Nguyen, M. I. Nisar, P. M. N. Pete, O. Norheim, Rosana E Norman, B. Norrving, L. Nyakarahuka, C. Obermeyer, F. Ogbo, I. Oh, O. Oladimeji, Pedro R Olivares, H. Olsen, B. Olusanya, J. Olusanya, John Nelson Opio, Eyal Oren, R. Orozco, Alberto Ortiz, E. Ota, Mahesh Pa, A. Pana, Eun‐Kee Park, C. Parry, M. Parsaeian, Tejas Patel, A. P. Caicedo, Snehal T. Patil, S. Patten, G. Patton, N. Pearce, David M Pereira, N. Perico, K. Pesudovs, M. Petzold, M. Phillips, F. Piel, J. Pillay, D. Plass, S. Polinder, C. Pond, C. Pope, D. Pope, S. Popova, R. Poulton, F. Pourmalek, N. Prasad, M. Qorbani, Rynaz Rabiee, A. Radfar, Anwar Rafay, V. Rahimi-Movaghar, Mahfuzar Rahman, Mohammad Hifz Ur Rahman, S. Rahman, R. Rai, Sasa Rajsic, M. Raju, U. Ram, S. Rana, K. Ranganathan, P. Rao, Christian García, A. Refaat, C. Rehm, J. Rehm, Nikolas Reinig, G. Remuzzi, S. Resnikoff, A. Ribeiro, J. Rivera, H. S. Roba, Alina Rodriguez, S. Rodríguez-Ramírez, D. Rojas-Rueda +499 moresemanticscholar +1 more source
