Results 241 to 250 of about 9,999,931 (293)

Rheumatoid factor and anticitrullinated protein antibody status jointly influence the association between disease activity and cardiovascular risk in rheumatoid arthritis. [PDF]

RMD Open
Karpouzas GA, Gonzalez-Gay MA, Pascual-Ramos V, Misra DP, Myasoedova E, Rantapää-Dahlqvist S, Sfikakis P, Dessein P, Hitchon CA, Galarza-Delgado D, Van Riel P, Semb AG, Hauge EM, Kitas GD, Ormseth SR, for An inTernationAl Cardiovascular Consortium for Rheumatoid Arthritis (ATACC-RA).   +15 more
europepmc   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Model-Dependent Cardiovascular Risk Stratification in Obese Populations: Multicenter Study in Türkiye. [PDF]

Int J Gen Med
Düzen Oflas N, Oral A, Solmaz I, Topaloglu US, Demir I, Dundar A, Kirik A, Kama Başcı O, Sen H, Binnetoglu E, Okuroglu N, Aydin A, Kaya ZI, Yıldız H, Acet A, Tazegül G, Sozel H, Ozudogru O, Issever K, Yaylacı S, Korkmaz UB, Küçük C, Konur K, Ayaz T, Isiklar A, Arac E, Sumbul HE, Öztürk HA, Govez AB, Durmus YÜ, Onmez A, Ocak Serin S, Koca N, Yalcın N, Ertinmaz A, Güven AT, Kok M, Alp HH, Sahinturk Y, Uyar S.   +39 more
europepmc   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Towards an Integrated Staging Model for Bipolar Disorders: An International Society for Bipolar Disorders (ISBD) Staging Task Force Consensus Report. [PDF]

Bipolar Disord
Kupka R, Hafeman D, McCallum M, van der Markt A, Tremain H, Alda M, Almeida J, Cardoso TA, Balanzá-Martínez V, Birmaher B, Bond DJ, Brietzke E, Chendo I, Grande I, Hajek T, Hillegers M, Kauer-Sant'Anna M, Mansur R, Passos IC, Pinto AG, Post R, Tohen M, Vazquez G, Vieta E, Yatham LN, Kapczinski F, Berk M, Duffy A.   +27 more
europepmc   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Fluoride varnish application and the temporal evolution of supragingival microbiota in children with differential caries risk. [PDF]

J Oral Microbiol
Liu F, Xue H, Jiang Y, Chen S, Zhang Y, Yu J, Qin Y, Dong X, Ou Y, Qiu R.   +9 more
europepmc   +1 more source

Spatio-temporal changes in clusters of gastric cancer incidence: The impact of nationwide cancer control programs in South Korea. [PDF]

PLoS One
Kim JH, Kim WK, Kim J, Kim SY.
europepmc   +1 more source

External validation of the VALE scoring system for hemorrhage risk in pediatric AVM patients. [PDF]

Neurosurg Rev
Kashefiolasl S, Porto L, Lachner K, Merker M, Schrewe R, Schubert-Bast S, Keil F, Prinz V, Finger T, Czabanka M.   +9 more
europepmc   +1 more source

Oxidized vitamin E metabolites during infancy and childhood asthma risk: too little, too much, or just right? [PDF]

Am J Respir Crit Care Med
Turi KN, Gebretsadik T, Rosas-Salazar C, Hartert TV.   +3 more
europepmc   +1 more source