Results 271 to 280 of about 25,767,497 (405)

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Beyond Glucose-Rethinking Prediabetes for Precision Prevention. [PDF]

Diabetes Care
Wagner R, Selvin E, Sehgal R, Prystupa K, Misra S, Fritsche A, Heni M.   +6 more
europepmc   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Decision, probability, and utility: Risk, ambiguity, and the Savage axioms

, 1988
D. Ellsberg
semanticscholar   +1 more source

Common polygenic variation contributes to risk of schizophrenia and bipolar disorder

Nature, 2009
S. Purcell, N. Wray, J. Stone, P. Visscher, M. O’Donovan, P. Sullivan, P. Sklar   +6 more
semanticscholar   +1 more source

Risk, Adultification, Messaging, and Protection Scale (RAMPS): The development of a measure for Black girls. [PDF]

J Res Adolesc
Crooks N, Snow-Hill N, Bushnell A, Sanker-Panchal K, Sissoko G.   +4 more
europepmc   +1 more source

Behavioral risk assessment in HIV Vaccine Trials Network (HVTN) clinical trials: A qualitative study exploring HVTN staff perspectives

, 2013
Michele P. Andrasik, Shelly Karuna, Michelle Nebergall, Beryl A. Koblin, J. Kublin   +4 more
openalex   +1 more source

Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node

FEBS Open Bio, EarlyView.
The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner, César G. Prucca, Lucia Boffelli, Virginia A. Piqueras, Silvia G. Correa, Mariana Maccioni, Mario E. Guido   +6 more
wiley   +1 more source

Risk of ischemic heart disease in women after radiotherapy for breast cancer.

New England Journal of Medicine, 2013
S. Darby, M. Ewertz, P. McGale, A. Bennet, U. Blom-Goldman, D. Brønnum, C. Correa, D. Cutter, Giovanna Gagliardi, B. Gigante, M. Jensen, A. Nisbet, R. Peto, K. Rahimi, Carolyn Taylor, P. Hall   +15 more
semanticscholar   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source