Results 91 to 100 of about 36,414,097 (422)

Dynamic Risk Assessment for Geologic CO2 Sequestration [PDF]

arXiv, 2021
At a geologic CO2 sequestration (GCS) site, geologic uncertainty usually leads to large uncertainty in the predictions of properties that influence metrics for leakage risk assessment, such as CO2 saturations and pressures in potentially leaky wellbores, CO2/brine leakage rates, and leakage consequences such as changes in drinking water quality in ...
arxiv  

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

Molecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi, Jérome Vialaret, Christophe Hirtz, Catherine Alix‐Panabières   +3 more
wiley   +1 more source

Peanut and hazelnut occurrence as allergens in foodstuffs with precautionary allergen labeling in Canada

npj Science of Food, 2021
Precautionary allergen labeling (PAL) is widely used by food industries. Occurrence studies revealed that few analyzed products contained the allergen(s) present in the statement, but little is known in Canada.
Emilie Manny, Sébastien La Vieille, Virginie Barrere, Jérémie Théolier, Samuel Benrejeb Godefroy   +4 more
doaj   +1 more source

Computer-Suported Risk Identification for the Holistic Management of Risks [PDF]

arXiv, 2015
Risk is part of the fabric of every business; surprisingly, there is little work on establishing best practices for systematic, repeatable risk identification, arguably the first step of any risk management process. In this paper, we present a proposal that constitutes a more holistic risk management approach, a methodology for computer-supported risk ...
arxiv  

Risk assessment at AGI companies: A review of popular risk assessment techniques from other safety-critical industries [PDF]

arXiv, 2023
Companies like OpenAI, Google DeepMind, and Anthropic have the stated goal of building artificial general intelligence (AGI) - AI systems that perform as well as or better than humans on a wide variety of cognitive tasks. However, there are increasing concerns that AGI would pose catastrophic risks.
arxiv  

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

Molecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker, Samantha Hasenleithner, Rupert Bartsch, Simon P. Gampenrieder, Daniel Egle, Christian F. Singer, Gabriel Rinnerthaler, Michael Hubalek, Katja Schmitz, Zsuzsanna Bago‐Horvath, Andreas Petzer, Sonja Heibl, Ellen Heitzer, Marija Balic, Michael Gnant   +14 more
wiley   +1 more source

Sensitivity analysis of Values at Risk [PDF]

Journal of Empirical Finance, 2000
The aim of this paper is to analyze the sensitivity of Value at Risk VaR with respect to portfolio allocation. We derive analytical expressions for the first and second derivatives of the VaR, and explain how they can be used to simplify statistical inference and to perform a local analysis of the VaR.
Gourieroux, Christian, Laurent, Jean-Paul, Scaillet, Olivier   +2 more
openaire   +8 more sources

Circulating tumor cells in metastatic breast cancer patients treated with immune checkpoint inhibitors – a biomarker analysis of the ALICE and ICON trials

Molecular Oncology, EarlyView.
In this explorative biomarker analysis, we assessed serial sampling of circulating tumor cells (CTCs) with CellSearch in two randomized trials testing immune checkpoint inhibitors (ICIs) in metastatic breast cancer. Our data demonstrate a prognostic potential of CTCs, most apparent 4 weeks into ICI therapy.
Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Elin Borgen, Cecilie Bendigtsen Schirmer, Bjørnar Gilje, Øystein Garred, Jon Lømo, Marius Stensland, Oddmund Nordgård, Ragnhild Sørum Falk, Randi R. Mathiesen, Hege G. Russnes, Jon Amund Kyte, Bjørn Naume   +13 more
wiley   +1 more source

The Natural Banach Space for Version Independent Risk Measures [PDF]

arXiv, 2013
Risk measures, or coherent measures of risk are often considered on the space L^\infty, and important theorems on risk measures build on that space. Other risk measures, among them the most important risk measure---the Average Value-at-Risk---are well defined on the larger space L^1 and this seems to be the natural domain space for this risk measure ...
arxiv  

Risk Analysis for the Infrastructure of a Hydrogen Economy [PDF]

, 2012
Increasing scarcity of fossil fuels makes the deployment of hydrogen in combination with renewable energy sources or the utilization of electricity from full time operation of existing power stations an interesting alternative.
Rosyid, O. A. (O)
core