Results 151 to 160 of about 4,430,078 (357)

A Risk Analysis of Risk Analysis [PDF]

open access: yes, 2007
Probabilistic risk or decision analysis is the most rigourous approach to engineering solutions to fiddicult diecision making problems involvingt uncertainty. A large body of theory and applications has been developed for probabilistic risk analysis, and
Lund, Jay R.
core   +1 more source

Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value

open access: yesMolecular Oncology, EarlyView.
The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song   +13 more
wiley   +1 more source

Recent advances in Raman technology with applications in agriculture, food and biosystems: A review

open access: yesArtificial Intelligence in Agriculture, 2019
Raman technology, which covers Raman spectroscopy (RS) and its various derivative methods, has been widely applied in detection of various substances in agriculture, food and biosystems.
Shizhuang Weng   +7 more
doaj  

Selection of Optimal Portfolio by Use of Risk Diversification Method [PDF]

open access: yes
The paper will discuss how securities investors can protect themselves from risk through diversification. There will be proposals how investors should structure their portfolio, i.e.
Ivan Kristek, Ivo Mijoc, Martina Bris
core  

Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi   +26 more
wiley   +1 more source

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

open access: yesMolecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam   +9 more
wiley   +1 more source

RAVEN: a GUI and an Artificial Intelligence Engine in a Dynamic PRA Framework [PDF]

open access: yes, 2013
Increases in computational power and pressure for more accurate simulations and estimations of accident scenario consequences are driving the need for Dynamic Probabilistic Risk Assessment (PRA) [1] of very complex models.
ALFONSI, ANDREA   +4 more
core  

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini   +10 more
wiley   +1 more source

Effect of Engineering and Management interventions on risk level of hazards in task of Emergency nurses shahid rahnamoon hospital of Yazd

open access: yesطب کار, 2020
Background: Emergency ward nurses exposed to occupational hazards. Job Safety Analysis (JSA) is a way to identify and assessment job-related risks and provide control strategies to reduce risks.
sanaz zibaei karizi   +3 more
doaj  

Quantifying Changes in Creativity: Findings from an Engineering Course on the Design of Complex and Origami Structures [PDF]

open access: yes, 2018
Engineering educators have increasingly sought strategies for integrating the arts into their curricula. The primary objective of this integration varies, but one common objective is to improve students’ creative thinking skills. In this paper, we sought
Anwar, Sohel   +5 more
core  

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