Results 91 to 100 of about 16,858,463 (407)

ISER 2012 Working Paper No. 1 [PDF]

open access: yes, 2012
Large resource development projects take years to plan. During that planning time, the public frequently debates the potential benefits and risks of a project, but with incomplete information.
Loeffler, Bob
core  

Structural dynamics of the plant hormone receptor ETR1 in a native‐like membrane environment

open access: yesFEBS Letters, EarlyView.
The present study unveils the structural and signaling dynamics of ETR1, a key plant ethylene receptor. Using an optimized nanodisc system and solution NMR, we captured full‐length ETR1 in a native‐like membrane environment. Our findings reveal dynamic domain uncoupling and Cu(I)‐induced rigidification, providing the first evidence of metal‐triggered ...
Moritz Lemke   +2 more
wiley   +1 more source

Novel and unscrutinized immune entities of the zebrafish gut

open access: yesFEBS Letters, EarlyView.
Understudied cells of the zebrafish immune system include bona fide immune cells and epithelial (‐derived) cells with immune functions. Research focusing on zebrafish cells which demonstrate similarities to mammalian immune cell counterparts may help us understand the pathologies in which they are implicated. Currently available and advanced tools make
Audrey Inge Schytz Andersen‐Civil   +5 more
wiley   +1 more source

Arsenic risk assessment. [PDF]

open access: yesEnvironmental Health Perspectives, 1994
We review recent publications by Hopenhayn-Rich et al. and Smith et al. regarding two critical issues in arsenic risk assessment: the role of methylation in the dose-response relationship and the role of internal cancers. Hopenhayn-Rich et al. applied simple linear regression to data from several studies to determine whether the percentage of inorganic
Heather Carlson-Lynch   +2 more
openaire   +4 more sources

Evaluating Future Dangerousness and Need for Treatment: The Roles of Expert Testimony, Attributional Complexity, and Victim Type [PDF]

open access: yes, 2013
In the current study, we explored the effect of risk-assessment testimony, attributional complexity, and victim type on participants’ perceptions of the dangerousness of a sexually violent person and his need for treatment. Participants read details of a
Gamache, Kyle   +2 more
core   +1 more source

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

open access: yesFEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona   +4 more
wiley   +1 more source

Risk assessment, prognosis and guideline implementation in pulmonary arterial hypertension

open access: yesEuropean Respiratory Journal, 2017
Current European guidelines recommend periodic risk assessment for patients with pulmonary arterial hypertension (PAH). The aim of our study was to determine the association between the number of low-risk criteria achieved within 1 year of diagnosis and ...
A. Boucly   +17 more
semanticscholar   +1 more source

Spatial models for flood risk assessment [PDF]

open access: yes, 2007
The problem of computing risk measures associated to flood events is extremely important not only from the point of view of civil protection systems but also because of the necessity for the municipalities of insuring against the damages. In this work we
Bee, Marco   +2 more
core  

The role of risk assessment in reducing homicides by people with mental illness [PDF]

open access: yes, 2000
Background: Improved risk assessment has been stressed as the way to reduce homicides by people with mental illness. The feasibility of predicting rare events needs examining.
Munro, Eileen, Rumgay, Judith
core   +1 more source

Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells

open access: yesFEBS Letters, EarlyView.
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura   +8 more
wiley   +1 more source

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