Results 121 to 130 of about 17,469,113 (405)
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Open the Jail Cell Doors, HAL: A Guarded Embrace of Pretrial Risk Assessment Instruments [PDF]
, 2018 In recent years, criminal justice reformers have focused their attention on pretrial detention as a uniquely solvable contributor to the horrors of modern mass incarceration. While reform of bail practices can take many forms, one of the most pioneering
Dalakian, Glen J., II
core +1 more source
A framework for complex climate change risk assessment
One Earth, 2021 N. Simpson +21 more
semanticscholar +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
The assessment of smart city information security risk in China based on zGT2FSs and IAA method [PDF]
, 2022 Hui Zhao, Yi‐Ting Wang, Xin Liu
openalex +1 more source
Risk Assessment and Sustainable Development: Towards a Concept of Sustainable Risk [PDF]
, 1997 Dr. Mehta examines two dominant approaches for managing health and environmental risks and suggests that they would better serve if ...
Mehta, Michael D.
core +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
La Medicina del lavoro, 2011 Erano le dodici di sabato 4 dicembre 2010. Dopo quattro giornate di congresso, i medici del lavoro avevano finalmente raggiunto l'orario fissato per ottenere i crediti formativi, e con la scheda delle risposte ai quiz diligentemente compilata si erano messi in fila davanti all'addetto al rilascio. Centinaia di medici, forse più di un migliaio, avevano
openaire +2 more sources
Algorithmic Risk Assessment in the Hands of Humans
Social Science Research Network, 2019 We evaluate the impacts of adopting algorithmic risk assessments in sentencing. We find that judges changed sentencing practices in response to the risk assessment, but that discretion played a large role in mediating its impact. Judges deviated from the
M. Stevenson, Jennifer L. Doleac
semanticscholar +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source