Results 121 to 130 of about 11,714,176 (315)

20220126_RAG_CST Communauté germanophone_FR

, 2022
RAG CST Communauté  ...
Risk Assessment Group
core  

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

20221107_RAG_PRA_Avian Influenza

, 2022
RAG rapport Avian Influenza 07-11 ...
Risk Assessment Group
core  

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Difference in ammonia air concentration at two sampling heights from ground surface: implications for deposition research

Atmospheric Environment: X
Monitoring atmospheric ammonia levels (NH3) is essential for accurately assessing nitrogen deposition, especially in agricultural regions. Conventional dry deposition measurement techniques are costly, complex, and often sparsely deployed, especially in ...
Claire Boerée-Kamphorst, Serigne Lô, Wietske Dohmen, Huifang Deng, Roel Vermeulen, Gerard Hoek, René Verburg, Dick Heederik   +7 more
doaj   +1 more source

20220817_RAG_Drempels barometer_NL

, 2022
RAG Drempels  ...
Risk Assessment Group
core  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Antimicrobial resistance in breeding pigs in Germany – differences between 2015 and 2023

Porcine Health Management
Background Direct contact with their offspring during the first few weeks makes sows a potential source of resistant bacteria for fattening pigs and food products derived from pigs.
Bernd-Alois Tenhagen, Tobias Lienen, Istvan Szabo, Carolina Plaza-Rodriguez, Mirjam Grobbel   +4 more
doaj   +1 more source

Analysis of the application of human milk oligosaccharides in hydrolyzed protein-based infant formula for special medical purposes

Zhongguo shipin weisheng zazhi
ObjectiveTo review and compare regulatory requirements and compliance considerations for the use of human milk oligosaccharides （HMOs） in food for special medical purposes intended for infants across major jurisdictions， and to appraise the mechanistic ...
JIN Zheyu, FANG Haiqin, LIANG Dong, WANG Qihe, LIU Sana, LI Huzhong, WANG Guo, XU Jiao   +7 more
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source