Results 151 to 160 of about 17,469,113 (405)
Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015
The Lancet, 2016 M. Forouzanfar, A. Afshin, Lily T Alexander, H. R. Anderson, Z. Bhutta, S. Biryukov, M. Brauer, R. Burnett, Kelly M. Cercy, F. Charlson, A. Cohen, L. Dandona, Kara Estep, A. Ferrari, J. Frostad, N. Fullman, P. Gething, W. Godwin, Max G Griswold, Simon Iain Hay, Y. Kinfu, H. Kyu, H. Larson, Xiaofeng Liang, Stephen S. Lim, Patrick Y. Liu, Alan D. Lopez, R. Lozano, L. Marczak, G. Mensah, A. Mokdad, M. Moradi-Lakeh, M. Naghavi, B. Neal, M. Reitsma, Gregory A. Roth, J. Salomon, P. Sur, T. Vos, Joseph A Wagner, Haidong Wang, Yi Zhao, Maigeng Zhou, Gunn Marit Aasvang, A. Abajobir, K. H. Abate, C. Abbafati, K. Abbas, F. Abd-Allah, A. Abdulle, S. Abera, Biju Abraham, L. Abu-Raddad, G. Abyu, A. Adebiyi, I. Adedeji, Z. Ademi, A. K. Adou, J. Adsuar, E. Agardh, A. Agarwal, Anurag Agrawal, A. Kiadaliri, O. Ajala, T. Akinyemiju, Z. Al-Aly, K. Alam, N. Alam, S. Aldhahri, R. Aldridge, Z. A. Alemu, R. Ali, A. Alkerwi, F. Alla, P. Allebeck, U. Alsharif, K. Altirkawi, E. A. Martin, N. Alvis-Guzmán, Azmeraw T. Amare, A. Amberbir, A. Amegah, H. Amini, W. Ammar, Stephen M. Amrock, H. Andersen, B. Anderson, C. Antonio, P. Anwari, J. Ärnlöv, A. Artaman, H. Asayesh, R. Asghar, Reza Assadi, S. Atique, Euripide Avokpaho, A. Awasthi, B. Quintanilla, P. Azzopardi, U. Bacha, A. Badawi, M. Bahit, K. Balakrishnan, A. Barać, Ryan Barber, S. Barker-Collo, T. Bärnighausen, S. Barquera, L. Barregard, L. Barrero, S. Basu, C. Batis, S. Bazargan-Hejazi, J. Beardsley, Neeraj Bedi, E. Beghi, B. Bell, M. Bell, A. Bello, D. Bennett, I. Benseñor, A. Berhane, E. Bernabé, B. Betsu, A. Beyene, N. Bhala, A. Bhansali, S. Bhatt, S. Biadgilign, B. Bikbov, D. Bisanzio, E. Bjertness, J. Blore, R. Borschmann, S. Boufous, R. Bourne, M. Brainin, A. Brazinova, N. Breitborde, H. Brenner, D. Broday, T. Brugha, B. Brunekreef, Z. Butt, L. Cahill, Bianca Calabria, Ismael Campos-Nonato, Rosario Cárdenas, D. Carpenter, J. Carrero, Daniel C. Casey, C. Castañeda-Orjuela, Jacqueline Castillo Rivas, R. Castro, F. Catalá-López, Jung-Chen Chang, P. Chiang, Mirriam Chibalabala, Odgerel Chimed-Ochir, V. Chisumpa, Abdulaal Chitheer, J. Choi, H. Christensen, D. Christopher, Liliana G. Ciobanu, M. Coates, Samantha M. Colquhoun, A. C. Manzano, Leslie T. Cooper, Kimberly Cooperrider, Leslie Cornaby, Monica Cortinovis, J. Crump, L. Cuevas-Nasu, A. Damasceno, R. Dandona, S. Darby, P. Dargan, J. D. das Neves, A. Davis, K. Davletov, E. F. de Castro, Vanessa De la Cruz-Góngora, D. de Leo, L. Degenhardt, Liana C. Del Gobbo, B. del Pozo-Cruz, R. Dellavalle, A. Deribew, D. Jarlais, S. Dharmaratne, P. Dhillon, C. Díaz-Torné, D. Dicker, E. Ding, E. Dorsey, Kerrie E. Doyle, T. Driscoll, L. Duan, M. Dubey, B. Duncan, I. Elyazar, A. Endries, S. Ermakov, H. Erskine, B. Eshrati, A. Esteghamati, S. Fahimi, E. J. Faraon, T. Farid, C. Farinha, Andre Faro, M. Farvid, F. Farzadfar, V. Feigin, S. Fereshtehnejad, J. Fernandes, F. Fischer, J. Fitchett, T. Fleming, N. Foigt, Kyle Foreman, F. Fowkes, R. Franklin, Thomas Fürst, N. Futran, E. Gakidou, A. García-Basteiro, T. Gebrehiwot, A. Gebremedhin, J. Geleijnse, B. Gessner, A. Z. Giref, M. Giroud, Melkamu Dedefo Gishu, G. Giussani, S. Goenka, M. Gómez-Cabrera, H. Gómez-Dantés, P. Gona, A. Goodridge, S. Gopalani, C. Gotay, A. Goto, H. Gouda, H. Gugnani, F. Guillemin, Yuming Guo, Rahul Gupta, Rajeev Gupta, R. A. Gutiérrez, J. Haagsma, N. Hafezi-Nejad, D. Haile, G. B. Hailu, Y. Halasa, R. Hamadeh, S. Hamidi, A. Handal, G. Hankey, Y. Hao, H. Harb, S. Harikrishnan, J. Haro, Mohammad Sadegh Hassanvand, T. A. Hassen, Rasmus J. Havmoeller, I. Heredia-Pi, N. Hernández-Llanes, P. Heydarpour, H. Hoek, H. Hoffman, M. Horino, N. Horita, H. Hosgood, D. Hoy, M. Hsairi, A. Htet, G. Hu, John J Emmanuel Huang, A. Husseini, S. Hutchings, I. Huybrechts, K. Iburg, B. Idrisov, B. Ileanu, M. Inoue, T. Jacobs, K. Jacobsen, N. Jahanmehr, M. Jakovljevic, H. Jansen, S. Jassal, Mehdi Javanbakht, S. Jayaraman, A. Jayatilleke, S. Jee, P. Jeemon, V. Jha, Ying Jiang, T. Jibat, Ye Jin, C. Johnson, J. Jonas, Z. Kabir, Y. Kalkonde, R. Kamal, H. Kan, A. Karch, C. Karema, Chante Karimkhani, A. Kasaeian, Anil Kaul, N. Kawakami, Dhruv S. Kazi, P. Keiyoro, L. Kemmer, A. Kemp, A. Kengne, A. Keren, C. Kesavachandran, Y. Khader, Abdur Rahman Khan, E. Khan, G. Khan, Y. Khang, S. Khatibzadeh, S. Khera, T. Khoja, J. Khubchandani, C. Kieling, Cho-il Kim, Daniel H. Kim, R. Kimokoti, N. Kissoon, M. Kivipelto, L. Knibbs, Y. Kokubo, J. Kopec, P. Koul, A. Koyanagi, M. Kravchenko, H. Kromhout, H. Krueger, Tiffany Ku, B. K. Defo, R. Kuchenbecker, B. K. Bicer, E. Kuipers, G. Kumar, G. Kwan, D. Lal, R. Lalloo, T. Lallukka, Q. Lan, A. Larsson, A. Latif, A. Lawrynowicz, J. Leasher, J. Leigh, J. Leung, M. Levi, Xiaohong Li, Yichong Li, Juan Liang, Shiwei Liu, B. Lloyd, G. Logroscino, P. Lotufo, R. Lunevicius, Michael F. MacIntyre, M. Mahdavi, M. Majdan, A. Majeed, R. Malekzadeh, D. Malta, Wondimu Ayele Ayele Manamo, C. Mapoma, W. Marcenes, R. Martin, J. Martínez-Raga, F. Masiye, K. Matsushita, R. Matzopoulos, B. Mayosi, J. Mcgrath, M. Mckee, P. Meaney, C. Medina, A. Mehari, Fabiola Mejía-Rodríguez, A. Mekonnen, Y. Melaku, Z. Memish, W. Mendoza, Gert B. M. Mensink, A. Meretoja, T. Meretoja, Y. Mesfin, F. Mhimbira, Anoushka I Millear, T. Miller, E. Mills, M. Mirarefin, A. Misganaw, C. Mock, A. Mohammadi, S. Mohammed, G. Mola, L. Monasta, J. M. Hernandez, M. Montico, L. Morawska, R. Mori, D. Mozaffarian, U. Mueller, Erin C. Mullany, J. Mumford, G. Murthy, J. Nachega, A. Naheed, V. Nangia, N. Nassiri, J. Newton, Marie Ng, Q. Nguyen, M. I. Nisar, P. M. N. Pete, O. Norheim, Rosana E Norman, B. Norrving, L. Nyakarahuka, C. Obermeyer, F. Ogbo, I. Oh, Olanrewaju Oladimeji, Pedro R Olivares, H. Olsen, B. Olusanya, J. Olusanya, John Nelson Opio, Eyal Oren, R. Orozco, Alberto Ortiz, E. Ota, Mahesh Pa, A. Pana, Eun‐Kee Park, C. Parry, M. Parsaeian, Tejas Patel, A. P. Caicedo, Snehal T. Patil, S. Patten, G. Patton, N. Pearce, David M Pereira, N. Perico, K. Pesudovs, M. Petzold, M. Phillips, F. Piel, J. Pillay, D. Plass, S. Polinder, C. Pond, C. Pope, D. Pope, S. Popova, R. Poulton, F. Pourmalek, N. Prasad, M. Qorbani, Rynaz Rabiee, A. Radfar, Anwar Rafay, V. Rahimi-Movaghar, Mahfuzar Rahman, Mohammad Hifz Ur Rahman, S. Rahman, R. Rai, Sasa Rajsic, M. Raju, U. Ram, S. Rana, K. Ranganathan, P. Rao, Christian García, A. Refaat, C. Rehm, J. Rehm, Nikolas Reinig, G. Remuzzi, S. Resnikoff, A. Ribeiro, J. Rivera, H. S. Roba, Alina Rodriguez, S. Rodríguez-Ramírez, D. Rojas-Rueda +499 moresemanticscholar +1 more sourceIn vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma
Molecular Oncology, EarlyView.Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni +14 morewiley +1 more sourceA comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010
The Lancet, 2012 Stephen S. Lim, T. Vos, A. Flaxman, G. Danaei, K. Shibuya, Heather Adair-Rohani, Mohammad A. Almazroa, M. Amann, H. R. Anderson, K. Andrews, M. Aryee, C. Atkinson, L. Bacchus, A. Bahalim, K. Balakrishnan, J. Balmes, S. Barker-Collo, A. Baxter, M. Bell, J. Blore, F. Blyth, C. Bonner, G. Borges, R. Bourne, M. Boussinesq, M. Brauer, P. Brooks, N. Bruce, B. Brunekreef, C. Bryan-Hancock, C. Bucello, R. Buchbinder, F. Bull, R. Burnett, T. Byers, Bianca Calabria, J. Carapetis, Emily Carnahan, Z. Chafe, F. Charlson, Honglei Chen, J. S. Chen, A. T. Cheng, J. C. Child, A. Cohen, K. Colson, B. Cowie, Sarah C. Darby, S. Darling, A. Davis, L. Degenhardt, F. Dentener, D. Jarlais, K. Devries, M. Dherani, E. Ding, E. Dorsey, T. Driscoll, K. Edmond, Suad Eltahir Ali, Rebecca E. Engell, P. Erwin, S. Fahimi, Gail Falder, F. Farzadfar, A. Ferrari, M. Finucane, S. Flaxman, F. Fowkes, Greg Freedman, Michael K. Freeman, E. Gakidou, Santu Ghosh, E. Giovannucci, G. Gmel, Kathryn Graham, R. Grainger, B. Grant, D. Gunnell, H. Gutierrez, Wayne Hall, H. Hoek, A. Hogan, H. Hosgood, D. Hoy, Howard Hu, B. Hubbell, S. Hutchings, Sydney E. Ibeanusi, G. Jacklyn, Rashmi Jasrasaria, J. Jonas, H. Kan, J. Kanis, N. Kassebaum, N. Kawakami, Y. Khang, S. Khatibzadeh, J. Khoo, Cindy Kok, F. Laden, R. Lalloo, Q. Lan, T. Lathlean, J. Leasher, J. Leigh, Yang Li, J. Lin, S. Lipshultz, S. London, R. Lozano, Yuan Lu, J. Mak, R. Malekzadeh, Leslie Mallinger, W. Marcenes, L. March, Robert G. Marks, R. Martin, P. McGale, J. Mcgrath, S. Mehta, Z. Memish, G. Mensah, T. Merriman, R. Micha, C. Michaud, V. Mishra, Khayriyyah Mohd Hanafiah, A. Mokdad, L. Morawska, D. Mozaffarian, Tasha B. Murphy, M. Naghavi, B. Neal, P. Nelson, J. Nolla, Rosana E Norman, Casey Olives, S. Omer, J. Orchard, R. Osborne, B. Ostro, A. Page, K. Pandey, C. Parry, E. Passmore, Jayadeep Patra, N. Pearce, P. Pelizzari, M. Petzold, M. Phillips, D. Pope, C. Pope, J. Powles, M. Rao, H. Razavi, E. Rehfuess, J. Rehm, B. Ritz, F. Rivara, Thomas J Roberts, Carolyn Robinson, J. A. Rodriguez-Portales, I. Romieu, R. Room, Lisa C Rosenfeld, Ananya Roy, L. Rushton, J. Salomon, Uchechukwu Sampson, L. Sànchez-Riera, Ella Sanman, A. Sapkota, S. Seedat, P. Shi, K. Shield, R. Shivakoti, Gitanjali M Singh, D. Sleet, Emma Smith, Kirk R. Smith, Nicolas J. C. Stapelberg, K. Steenland, H. Stöckl, L. Stovner, K. Straif, L. Straney, G. Thurston, Jimmy H. Tran, R. Dingenen, A. Donkelaar, J. Veerman, L. Vijayakumar, Robert Weintraub, M. Weissman, Richard A. White, H. Whiteford, S. Wiersma, J. Wilkinson, H. Williams, Warwick Williams, N. Wilson, A. Woolf, P. Yip, J. Zielinski, Alan D. Lopez, C. Murray, M. Ezzati +208 moresemanticscholar +1 more sourcePatient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert +16 morewiley +1 more sourcePredictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia
Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman +17 morewiley +1 more source
