Results 251 to 260 of about 17,469,113 (405)

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Commodity risk assessment of oak and walnut logs from the US. [PDF]

EFSA J
EFSA Panel on Plant Health (PLH), Vicent Civera A, Baptista P, Berlin A, Chatzivassiliou E, Cubero J, Cunniffe N, de la Peña E, Desneux N, Di Serio F, Filipiak A, Hasiów-Jaroszewska B, Jactel H, Landa BB, Maistrello L, Makowski D, Milonas P, Papadopoulos NT, Potting R, Susi H, van Der Gaag DJ, Battisti A, Bragard C, Mas H, Rigling D, Faccoli M, Mikulová A, Stergulc F, Mosbach-Schulz O, Streissl F, Gonthier P.   +30 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Assessment of Antihelminthic Efficacy of Mebendazole 500 mg against Soil- Transmitted Helminths in a High Risk Area of Cameroon

, 2017
Ngo Ngué Thérése Nadyne, Nkengazong Lucia, Thérèse Nkoa, Adamou Mfopa, Ngué Monique, Motsebo Amede, Moyou- Somo Roger, Nukenine Elias Nchiwan   +7 more
openalex   +1 more source

Health Risk Assessment of Dietary Chemical Exposures: A Comprehensive Review. [PDF]

Foods
Pekmezci H, Sipahi S, Başaran B.
europepmc   +1 more source

COMPAS Risk Assessment - FUSL000014 (2016-03-03) [PDF]

, 2019

core   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Risk assessment of the presence of various organic and inorganic compounds in oil flows in different units of refineries by methods of FMEA and PHA [PDF]

, 2019
Mehrzad Zandieh
openalex   +1 more source

Occurrence, environmental correlates, and risk assessment of Vibrio parahaemolyticus in Caspian sea coastal waters. [PDF]

Sci Rep
Ahmadi M, Esrafili A, Pazoki-Toroudi H, Gorjipour F, Rezaei Kalantary R.   +4 more
europepmc   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source