Results 41 to 50 of about 3,055,986 (315)

Advancing the Contribution of Occupational Epidemiology to Risk Assessment [PDF]

, 2011
The identification and quantification of risk factors that are characterized by low exposure levels, moderately increased risks, and unspecific exposure-disease relations is a major challenge facing risk assessment today.
Vlaanderen, J.J., Dep IRAS, Risk Assessment of Toxic and Immunomodulatory Agents   +2 more
core  

Challenges of quantitative microbial risk assessment at EU level. [PDF]

, 2009
Quantitative microbial risk assessment (QMRA) aims to model the fate of pathogenic micro-organisms along the food chain and the associated health risks.
Evers, E.G., Nauta, M.J., Dep IRAS, Risk Assessment of Toxic and Immunomodulatory Agents, Havelaar, A.H.   +4 more
core  

Probabilistic cumulative risk assessment of anti-androgenic pesticides in food [PDF]

, 2008
In this paper, we present a cumulative risk assessment of three anti-androgenic pesticides (vinclozolin, procymidone and prochloraz) using the relative potency factor (RPF) approach and an integrated probabilistic risk assessment (IPRA) model.
Nielsen, E., Dep IRAS, Ladefoged, O., Bosgra, S., Voet, H. van der, Risk Assessment of Toxic and Immunomodulatory Agents, Boon, P. E., Boon, P.E., Müller, Anne Kirstine, Boon, Polly E., van der Voet, Hilko, Bosgra, Sieto, Voet, H., van der, Ladefoged, Ole, Nielsen, Elsa, van der Voet, H., Müller, A.K.   +16 more
core   +1 more source

Are Fertility Preservation Procedures Before Gonadotoxic Therapy and Hematopoietic Stem Cell Transplantation Feasible and Safe in Very Young Children? A Retrospective Cohort Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Fertility preservation (FP) is increasingly integrated into the care of pediatric patients exposed to gonadotoxic therapy or conditioning for hematopoietic stem cell transplantation (HSCT), yet perioperative data in infants and toddlers remain scarce.
Kerstin Saalabian, Yannick Braun, Till‐Martin Theilen, Anke Barnbrock, Theresa Rohm, Fabienne Hammant, Nicole Sänger, Aynura Abbasova‐Semiz, Jan‐Henning Klusmann, Thomas Klingebiel, Udo Rolle, Peter Bader, Henning C. Fiegel, Andrea Jarisch   +13 more
wiley   +1 more source

Evaluating uncertainties in an integrated approach for chemical risk assessment under REACH: more certain decisions? [PDF]

, 2009
This thesis concentrates on uncertainty and variability in the risk assessment methodology for industrial chemicals as applied within the current regulatory framework for industrial chemicals in Europe, REACH (Registration, Evaluation, Authorisation and ...
Vermeire, T.G., Dep IRAS, Risk Assessment of Toxic and Immunomodulatory Agents   +2 more
core  

Central Nervous System Neuroblastoma, FOXR2‐Activated: A Pooled Analysis of Published Clinical Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) neuroblastoma, FOXR2‐activated, is a recently recognized entity in the WHO CNS5 classification, defined by activation of the FOXR2 transcription factor and unique histopathological features. This review synthesizes available literature and pooled clinical data, providing insight into demographics ...
Sudarshawn Damodharan, Mohamed S. Abdelbaki   +1 more
wiley   +1 more source

Exploration on the establishment of a food contaminants standards evaluation index system based on the Delphi method

Zhongguo shipin weisheng zazhi
ObjectiveTo explore the establishment of a food contaminants standards evaluation index system using the delphi method， and to provide certain reference basis for systematic evaluation and scientific improvement of food contaminant standards ...
LIANG Shiyuan, CHEN Xiao, DONG Xiaoze, WANG Jun, SHAO Yi   +4 more
doaj   +1 more source

Development of Sensitive and Reliable UPLC-MS/MS Methods for Food Analysis of Emerging Mycotoxins in China Total Diet Study

Toxins, 2019
With the climatic changes that have taken place during the last decade, the spectrum of fungal pathogens as well as mycotoxins has considerably changed.
Danlei Sun, Nannan Qiu, Shuang Zhou, Bing Lyu, Shuo Zhang, Jingguang Li, Yunfeng Zhao, Yongning Wu   +7 more
doaj   +1 more source

Prevalence of 21 Physician‐Defined Severe Toxicities Following Childhood Acute Lymphoblastic Leukemia Treatment: Australian Retrospective Cohort Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer, with an overall survival now surpassing 90% in developed countries. However, treatments are not without adverse effects. In this study, we apply the severe toxicity‐free survival (STFS) framework to determine the prevalence of 21 physician‐defined severe ...
Lane Collier, Brittany Grantham, Camilla Grud Nielsen, Louise Lundgren, Liv Andrés‐Jensen, Kjeld Schmiegelow, Chris Selman, Gareth Ball, Elyse Passmore, David A. Elliott, Rachel Conyers   +10 more
wiley   +1 more source

Sustained Therapeutic Efficacy of Intravenous Plasminogen Concentrate in Pediatric Patients With Type 1 Plasminogen Deficiency: An Analysis of Dosing Parameters and Clinical Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Type 1 plasminogen deficiency (PLGD‐1) is an ultra‐rare autosomal recessive disorder caused by variants in the PLG gene and affects approximately 1.6 individuals per million. The condition is characterized by decreased plasminogen levels and impaired function, resulting in fibrin‐rich lesions on mucous membranes throughout the body.
Charles Nakar, Karen Thibaudeau, Mary Mathias, Heather McDaniel, Madlen Reschke, Klaus Tenbrock, Joseph M. Parker, Amy Shapiro   +7 more
wiley   +1 more source