Results 71 to 80 of about 10,758,089 (294)

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

BIKE: Dietary Exposure Model for Foodborne Microbiological and Chemical Hazards

open access: yesFoods, 2021
BIKE is a Bayesian dietary exposure assessment model for microbiological and chemical hazards. A graphical user interface was developed for running the model and inspecting the results.
Jukka Ranta   +3 more
doaj   +1 more source

NCCN Guidelines Insights: Genetic/Familial High-Risk Assessment: Colorectal, Version 2.2019.

open access: yesThe Journal of the National Comprehensive Cancer Network, 2019
Identifying individuals with hereditary syndromes allows for improved cancer surveillance, risk reduction, and optimized management. Establishing criteria for assessment allows for the identification of individuals who are carriers of pathogenic genetic ...
Samir Gupta   +28 more
semanticscholar   +1 more source

Social context prevents heat hormetic effects against mutagens during fish development

open access: yesFEBS Letters, EarlyView.
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere   +5 more
wiley   +1 more source

Establishment of probability assessment parameters of consumption of alcoholic beverage based on the contact area

open access: yesZhongguo shipin weisheng zazhi, 2022
ObjectiveTo support the probabilistic assessment of food contact materials with consumption parameters and methodology, the establishment of consumption data based on food contact area with different types of alcoholic beverages and different food ...
LI Shan   +5 more
doaj   +1 more source

Autophagy in cancer and protein conformational disorders

open access: yesFEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

The risk in risk assessment [PDF]

open access: yesThe Psychiatrist, 2013
Szmukler et al [1][1] should be warmly congratulated on their clear, authoritative critique of the recent developments in the law of England and Wales concerning mental health. Their analysis of the assessment of risk is particularly telling: ‘Rare events are virtually impossible to predict ...
openaire   +1 more source

A stepwise emergence of evolution in the RNA world

open access: yesFEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

[Risk assessment].

open access: yesLa Medicina del lavoro, 2011
Erano le dodici di sabato 4 dicembre 2010. Dopo quattro giornate di congresso, i medici del lavoro avevano finalmente raggiunto l'orario fissato per ottenere i crediti formativi, e con la scheda delle risposte ai quiz diligentemente compilata si erano messi in fila davanti all'addetto al rilascio. Centinaia di medici, forse più di un migliaio, avevano
openaire   +5 more sources

The risks of risk assessment [PDF]

open access: yesAdvances in Psychiatric Treatment, 2007
Risk assessment has become a large and anxiety-provoking part of the work of many psychiatrists. This article unpicks the different meanings of the word ‘risk’ to seek out the source of that anxiety, looking at both statistical and sociological ideas about risk.
openaire   +2 more sources

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