Results 231 to 240 of about 171,618 (292)

Psychedelics as pharmacotherapeutics for substance use disorders: A scoping review on clinical trials and perspectives on underlying neurobiology

open access: yesBritish Journal of Pharmacology, EarlyView.
Theorized mechanism of dopamine homeostasis restoration in the nucleus accumbens core induced by a psychedelic intervention. Abstract Psychedelics have garnered great attention in recent years as treatments for major depressive disorder (MDD) and treatment‐resistant depression because of their ability to alter consciousness and afflicted cognitive ...
Lucas Wittenkeller   +3 more
wiley   +1 more source

Network analysis of school absence: central symptoms and their functions. [PDF]

open access: yesFront Child Adolesc Psychiatry
Alanko K   +3 more
europepmc   +1 more source

TRP canonical 4 and/or 5 channel inhibition reduces aversion‐ and increases reward‐responding in chronically stressed mice

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Pharmacological inhibition of TRPC4 and/or TRPC5 channels reduces Pavlovian aversion memory in stressed mice and reduces amygdala reactivity to aversion in humans with depression. The aims of this mouse study were to improve understanding of these anxiolytic processes, determine whether there are corrective effects on ...
Giulia Poggi   +14 more
wiley   +1 more source

Homo sapiens, industrialisation and the environmental mismatch hypothesis

open access: yesBiological Reviews, EarlyView.
ABSTRACT For the vast majority of the evolutionary history of Homo sapiens, a range of natural environments defined the parameters within which selection shaped human biology. Although human‐induced alterations to the terrestrial biosphere have been evident for over 10,000 years, the pace and scale of change has accelerated dramatically since the onset
Daniel P. Longman, Colin N. Shaw
wiley   +1 more source

Measuring Lead Userness: Development and Validation of a Hierarchical Scale

open access: yesCreativity and Innovation Management, Volume 34, Issue 4, Page 944-962, December 2025.
ABSTRACT Lead user theory has gained traction in both academia and practice, given that involving lead users (LUs) can yield more innovative and commercially successful products. Yet, measurement inconsistencies have hindered consensus on how to reliably assess lead userness.
Moritz Paulus   +3 more
wiley   +1 more source

Protective but Costly: The Impact of Behavioral Immune System Reactivity on Mental Health. [PDF]

open access: yesInt J Environ Res Public Health
Hromatko I   +5 more
europepmc   +1 more source

Cost‐Effectiveness of Applying Fluoride Varnish to Preschoolers in a Brazilian Scenario: An Economic Modelling Study

open access: yesCommunity Dentistry and Oral Epidemiology, EarlyView.
ABSTRACT Background International economic evaluations have not found convincing evidence that the application of fluoride varnish (FV) in preschool children is a cost‐effective anti‐caries measure, and there is a lack of economic evaluations of FV in the Brazilian context.
Izabel Monteiro Dhyppolito   +3 more
wiley   +1 more source

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