Results 151 to 160 of about 6,865,417 (306)

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Utilization of Training for Nurses in the Prevention of Adolescent Violence Risk Behaviors: Protocol for a Scoping Review. [PDF]

JMIR Res Protoc
Maryatun S, Nurjannah I, Pertiwi AAP.
europepmc   +1 more source

Sociology of Leisure: Risk and Leisure RLO

, 2010
This RLO is part of “Sociology of Leisure” course. The module discusses some major features of current leisure patterns, but these activities are also central to modern life itself and thus have interests for sociologists.
Dr Dave Harris, MARJON
core  

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

ChatGPT in Healthcare Writing: Advantages and Limitations [PDF]

Healthcare Informatics Research
SeyedAhmad SeyedAlinaghi, Pegah Mirzapour, Esmaeil Mehraeen   +2 more
doaj   +1 more source

Modeling Heterogeneity in Health Risk Behaviors With a Dynamic Mixture Model Informed by Textual Occupational Data. [PDF]

Stat Med
Schiavon L, Stival M, Andreella A, Campostrini S.   +3 more
europepmc   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Ethical Considerations for AI Use in Healthcare Research [PDF]

Healthcare Informatics Research
SeyedAhmad SeyedAlinaghi, Pedram Habibi, Esmaeil Mehraeen   +2 more
doaj   +1 more source

Latent class profiles of health-risk behaviors and the protective roles of psychological resilience and self-control in Chinese adolescents. [PDF]

Front Public Health
Liu L, Chen J, Wang Y, Xu T.
europepmc   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source