Results 181 to 190 of about 24,883,480 (353)

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Analysis of promoter region polymorphism in the aldosterone synthase gene (CYP11B2) as a risk factor for myocardial infarction [PDF]

, 2000
Shilpa Patel, Richard P. Steeds, KS Channer, Nilesh J. Samani   +3 more
openalex   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Flecainide and elevated liver enzymes in α1-antitrypsin deficiency

HeartRhythm Case Reports, 2016
David J.A. Jenkins, MD, PhD, FRCP, Michael Freeman, MD, FRCPC, Iqwal Mangat, MD, FRCPC, Koruba Srichaikul, MD, MSc, Viranda H. Jayalath, MSc, Dorothea Faulkner, RD, PhD, John L. Sievenpiper, MD, PhD, FRCPC, Cyril W.C. Kendall, PhD, Alexander Romaschin, PhD, Young-In Kim, MD, FRCPC, Paul Dorian, MD, FRCPC, FHRS   +10 more
doaj   +1 more source

Is Radiotherapy a Risk Factor for Melanoma? [PDF]

Dermatopathology (Basel)
Ozer S, Agarwal P, Musolff N, Plann-Curley B, Cosgun G, Sun HY, Rao B.   +6 more
europepmc   +1 more source

Is lipoprotein(a) a risk factor for ischemic stroke and venous thromboembolism? [PDF]

, 2019
Alexander H. Nave, Arnold von Eckardstein   +1 more
openalex   +1 more source

The projected effect of risk factor reduction on Alzheimer's disease prevalence

Lancet Neurology, 2011
D. Barnes, K. Yaffe
semanticscholar   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Hypertension - a major modifiable and undertreated risk factor. [PDF]

Aust Prescr
Hespe C, Stocks N, Nelson M.
europepmc   +1 more source

Cognitive Decline in Adults Aged 65 and Older in Cumbayá, Quito, Ecuador: Prevalence and Risk Factors [PDF]

, 2018
Patricio H Espinosa del Pozo, Patricio S Espinosa, Eduardo Antônio Donadi, Edson Zangiacomí Martínez, Juan Carlos Salazar, Marco Guerrero, Júlio César Moriguti, Mishell C Colcha, Susana E Garcia, Raquel Naranjo, Wilson E Altamirano, Adriana Y Koek   +11 more
openalex   +1 more source