Results 231 to 240 of about 6,770,863 (365)

Narcolepsy as a potential risk factor for Schizophrenia. [PDF]

open access: yesTransl Psychiatry
Eghtedarian R   +6 more
europepmc   +1 more source

Risk factor modification

open access: yesJournal of the American College of Cardiology, 1985
openaire   +3 more sources

Positive feedback loop between MAPK and aquaporin 7 regulates autophagy and apoptosis induced by palmitate in RIN‐m5f cells

open access: yesFEBS Open Bio, EarlyView.
T2DM is characterized by peripheral blood insulin resistance and progressive pancreatic β‐cell dysfunction. Here, we showed that AQP7, the only aquaglyceroporin protein, regulates autophagy and apoptosis in pancreatic β‐cells. We propose the existence of a positive feedback loop between MAPK signaling and AQP7 that regulates autophagy and apoptosis in ...
Maoqi Wang   +5 more
wiley   +1 more source

Pancreatic Status Is Not a Risk Factor for Cystic Fibrosis-Related Bone Disease. [PDF]

open access: yesPediatr Pulmonol
Dotan M   +6 more
europepmc   +1 more source

Enhancing transporter activity in heterologous expression systems with SAHA: a 2500‐times more potent and odorless alternative to butyrate

open access: yesFEBS Open Bio, EarlyView.
Heterologous expression of membrane transporters in cultured cells is essential for functional characterization, but is sometimes limited by low activity. Our study compares the HDAC inhibitors butyrate, VPA and SAHA to enhance transport activity. We propose to replace butyrate by SAHA: it is equally effective, devoid of repulsive odor, costs less, and
Svenja Flögel   +4 more
wiley   +1 more source

Nicotinamide adenine dinucleotide phosphate oxidase 2 deletion attenuates polyhexamethylene guanidine-induced lung injury in mice

open access: yesHeliyon
Inhalation of polyhexamethylene guanidine phosphate (PHMG) can cause pulmonary fibrosis. Nicotinamide adenine dinucleotide phosphate (NADPH) oxidases (Nox) are enzymes that produce reactive oxygen species, which may be involved in tissue damage in ...
Yoon Cho   +9 more
doaj  

Lipoprotein(a) as a Causal Risk Factor for Cardiovascular Disease. [PDF]

open access: yesCurr Cardiovasc Risk Rep
Doherty S   +7 more
europepmc   +1 more source

Comparative single‐cell transcriptomic profiling of patient‐derived renal carcinoma cells in cellular and animal models of kidney cancer

open access: yesFEBS Open Bio, EarlyView.
We generated and characterized clear cell renal cell carcinoma models using the patient‐derived RCC243 cell line—including cell culture, orthotopic, and metastatic tumors—via single‐cell RNA‐sequencing for comparisons between models and patient tumor datasets.
Richard Huang   +9 more
wiley   +1 more source

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